Successful treatment of leptomeningeally metastasised pituitary carcinoma with temozolomide

A. van Der Vlist; T. J. Snijders; A. M.E. Stades; W. G.M. Spliet; F. Y.F.L. De Vos

Successful treatment of leptomeningeally metastasised pituitary carcinoma with temozolomide

A. van Der Vlist
, T. J. Snijders
, A. M.E. Stades
, W. G.M. Spliet
, F. Y.F.L. De Vos^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

A 69-year-old man presented with leptomeningeally metastasised pituitary carcinoma, rapidly progressing despite previous treatment with resection, radiotherapy and cabergoline. The patient received temozolomide chemotherapy, resulting in a complete clinical, radiological and biochemical response after 14 cycles, which has been maintained since then. This case lends further support to the role of temozolomide in refractory pituitary tumours.

Original language	English
Pages (from-to)	451-454
Number of pages	4
Journal	Netherlands Journal of Medicine
Volume	75
Issue number	10
Publication status	Published - Dec 2017

Keywords

Pituitary carcinoma
Prolactinoma
Temozolomide

Cite this

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title = "Successful treatment of leptomeningeally metastasised pituitary carcinoma with temozolomide",

abstract = "A 69-year-old man presented with leptomeningeally metastasised pituitary carcinoma, rapidly progressing despite previous treatment with resection, radiotherapy and cabergoline. The patient received temozolomide chemotherapy, resulting in a complete clinical, radiological and biochemical response after 14 cycles, which has been maintained since then. This case lends further support to the role of temozolomide in refractory pituitary tumours.",

keywords = "Pituitary carcinoma, Prolactinoma, Temozolomide",

author = "\{van Der Vlist\}, A. and Snijders, \{T. J.\} and Stades, \{A. M.E.\} and Spliet, \{W. G.M.\} and \{De Vos\}, \{F. Y.F.L.\}",

year = "2017",

month = dec,

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TY - JOUR

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AU - van Der Vlist, A.

AU - Snijders, T. J.

AU - Stades, A. M.E.

AU - Spliet, W. G.M.

AU - De Vos, F. Y.F.L.

PY - 2017/12

Y1 - 2017/12

N2 - A 69-year-old man presented with leptomeningeally metastasised pituitary carcinoma, rapidly progressing despite previous treatment with resection, radiotherapy and cabergoline. The patient received temozolomide chemotherapy, resulting in a complete clinical, radiological and biochemical response after 14 cycles, which has been maintained since then. This case lends further support to the role of temozolomide in refractory pituitary tumours.

AB - A 69-year-old man presented with leptomeningeally metastasised pituitary carcinoma, rapidly progressing despite previous treatment with resection, radiotherapy and cabergoline. The patient received temozolomide chemotherapy, resulting in a complete clinical, radiological and biochemical response after 14 cycles, which has been maintained since then. This case lends further support to the role of temozolomide in refractory pituitary tumours.

KW - Pituitary carcinoma

KW - Prolactinoma

KW - Temozolomide

UR - https://www.scopus.com/pages/publications/85038868818

M3 - Article

C2 - 29256415

SN - 0300-2977

VL - 75

SP - 451

EP - 454

JO - Netherlands Journal of Medicine

JF - Netherlands Journal of Medicine

IS - 10

ER -

Successful treatment of leptomeningeally metastasised pituitary carcinoma with temozolomide

Abstract

Keywords

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