Successful treatment of leptomeningeally metastasised pituitary carcinoma with temozolomide

A. van Der Vlist, T. J. Snijders, A. M.E. Stades, W. G.M. Spliet, F. Y.F.L. De Vos*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

A 69-year-old man presented with leptomeningeally metastasised pituitary carcinoma, rapidly progressing despite previous treatment with resection, radiotherapy and cabergoline. The patient received temozolomide chemotherapy, resulting in a complete clinical, radiological and biochemical response after 14 cycles, which has been maintained since then. This case lends further support to the role of temozolomide in refractory pituitary tumours.

Original languageEnglish
Pages (from-to)451-454
Number of pages4
JournalNetherlands Journal of Medicine
Volume75
Issue number10
Publication statusPublished - Dec 2017

Keywords

  • Pituitary carcinoma
  • Prolactinoma
  • Temozolomide

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