Studies on the mechanism of polyuria induced by cortisol excess in the dog.

J. A. Joles; A. Rijnberk; W. E. van den Brom; J. Dogterom

Studies on the mechanism of polyuria induced by cortisol excess in the dog.

J. A. Joles^*, A. Rijnberk, W. E. van den Brom, J. Dogterom

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

3 Citations (Scopus)

Abstract

Water balance studies were performed in 7 experimental dogs before and during a period of cortisol-induced polyuria and in one dog with spontaneous hyperadrenocorticism before and after removal of an adrenocortical carcinoma. Measurements of urine and plasma osmolality and plasma arginine vasopressin concentration were made at regular intervals during the water deprivation studies. The results indicate that cortisol does not block the release of vasopressin but interferes with its action in the kidney.

Original language	English
Pages (from-to)	199-205
Number of pages	7
Journal	Tijdschrift voor Diergeneeskunde
Volume	105
Issue number	20
Publication status	Published - 15 Oct 1980
Externally published	Yes

Cite this

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AU - Dogterom, J.

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Studies on the mechanism of polyuria induced by cortisol excess in the dog.

Abstract

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