Stereotactic Body Radiotherapy in Recurrent and Oligometastatic Head and Neck Tumours

Jodie L.M. Tham; Sweet Ping Ng; Richard Khor; Morikatsu Wada; Hui Gan; Alesha A. Thai; June Corry; Houda Bahig; Antti A. Mäkitie; Sandra Nuyts; Remco De Bree; Primož Strojan; Wai Tong Ng; Avraham Eisbruch; James C.H. Chow; Alfio Ferlito

doi:10.3390/jcm13113020

Stereotactic Body Radiotherapy in Recurrent and Oligometastatic Head and Neck Tumours

Jodie L.M. Tham^*, Sweet Ping Ng^*, Richard Khor, Morikatsu Wada, Hui Gan, Alesha A. Thai, June Corry, Houda Bahig, Antti A. Mäkitie, Sandra Nuyts, Remco De Bree, Primož Strojan, Wai Tong Ng, Avraham Eisbruch, James C.H. Chow, Alfio Ferlito

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

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Abstract

The treatment of head and neck cancers (HNCs) encompasses a complex paradigm involving a combination of surgery, radiotherapy, and systemic treatment. Locoregional recurrence is a common cause of treatment failure, and few patients are suitable for salvage surgery. Reirradiation with conventional radiation techniques is challenging due to normal tissue tolerance limits and the risk of significant toxicities. Stereotactic body radiotherapy (SBRT) has emerged as a highly conformal modality that offers the potential for cure while limiting the dose to surrounding tissue. There is also growing research that shows that those with oligometastatic disease can benefit from curative intent local ablative therapies such as SBRT. This review will look at published evidence regarding the use of SBRT in locoregional recurrent and oligometastatic HNCs.

Original language	English
Article number	3020
Number of pages	19
Journal	Journal of Clinical medicine
Volume	13
Issue number	11
DOIs	https://doi.org/10.3390/jcm13113020
Publication status	Published - Jun 2024
Externally published	Yes

Keywords

head and neck cancer
oligometastatic
recurrent
reirradiation
stereotactic body radiotherapy

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10.3390/jcm13113020Licence: CC BY

jcm-13-03020Final published version, 318 KBLicence: CC BY

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Tham, J. L. M., Ng, S. P., Khor, R., Wada, M., Gan, H., Thai, A. A., Corry, J., Bahig, H., Mäkitie, A. A., Nuyts, S., De Bree, R., Strojan, P., Ng, W. T., Eisbruch, A., Chow, J. C. H., & Ferlito, A. (2024). Stereotactic Body Radiotherapy in Recurrent and Oligometastatic Head and Neck Tumours. Journal of Clinical medicine, 13(11), Article 3020. https://doi.org/10.3390/jcm13113020

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abstract = "The treatment of head and neck cancers (HNCs) encompasses a complex paradigm involving a combination of surgery, radiotherapy, and systemic treatment. Locoregional recurrence is a common cause of treatment failure, and few patients are suitable for salvage surgery. Reirradiation with conventional radiation techniques is challenging due to normal tissue tolerance limits and the risk of significant toxicities. Stereotactic body radiotherapy (SBRT) has emerged as a highly conformal modality that offers the potential for cure while limiting the dose to surrounding tissue. There is also growing research that shows that those with oligometastatic disease can benefit from curative intent local ablative therapies such as SBRT. This review will look at published evidence regarding the use of SBRT in locoregional recurrent and oligometastatic HNCs.",

keywords = "head and neck cancer, oligometastatic, recurrent, reirradiation, stereotactic body radiotherapy",

author = "Tham, {Jodie L.M.} and Ng, {Sweet Ping} and Richard Khor and Morikatsu Wada and Hui Gan and Thai, {Alesha A.} and June Corry and Houda Bahig and M{\"a}kitie, {Antti A.} and Sandra Nuyts and {De Bree}, Remco and Primo{\v z} Strojan and Ng, {Wai Tong} and Avraham Eisbruch and Chow, {James C.H.} and Alfio Ferlito",

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month = jun,

doi = "10.3390/jcm13113020",

language = "English",

volume = "13",

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AU - Tham, Jodie L.M.

AU - Ng, Sweet Ping

AU - Khor, Richard

AU - Wada, Morikatsu

AU - Gan, Hui

AU - Thai, Alesha A.

AU - Corry, June

AU - Bahig, Houda

AU - Mäkitie, Antti A.

AU - Nuyts, Sandra

AU - De Bree, Remco

AU - Strojan, Primož

AU - Ng, Wai Tong

AU - Eisbruch, Avraham

AU - Chow, James C.H.

AU - Ferlito, Alfio

PY - 2024/6

Y1 - 2024/6

N2 - The treatment of head and neck cancers (HNCs) encompasses a complex paradigm involving a combination of surgery, radiotherapy, and systemic treatment. Locoregional recurrence is a common cause of treatment failure, and few patients are suitable for salvage surgery. Reirradiation with conventional radiation techniques is challenging due to normal tissue tolerance limits and the risk of significant toxicities. Stereotactic body radiotherapy (SBRT) has emerged as a highly conformal modality that offers the potential for cure while limiting the dose to surrounding tissue. There is also growing research that shows that those with oligometastatic disease can benefit from curative intent local ablative therapies such as SBRT. This review will look at published evidence regarding the use of SBRT in locoregional recurrent and oligometastatic HNCs.

AB - The treatment of head and neck cancers (HNCs) encompasses a complex paradigm involving a combination of surgery, radiotherapy, and systemic treatment. Locoregional recurrence is a common cause of treatment failure, and few patients are suitable for salvage surgery. Reirradiation with conventional radiation techniques is challenging due to normal tissue tolerance limits and the risk of significant toxicities. Stereotactic body radiotherapy (SBRT) has emerged as a highly conformal modality that offers the potential for cure while limiting the dose to surrounding tissue. There is also growing research that shows that those with oligometastatic disease can benefit from curative intent local ablative therapies such as SBRT. This review will look at published evidence regarding the use of SBRT in locoregional recurrent and oligometastatic HNCs.

KW - head and neck cancer

KW - oligometastatic

KW - recurrent

KW - reirradiation

KW - stereotactic body radiotherapy

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U2 - 10.3390/jcm13113020

DO - 10.3390/jcm13113020

M3 - Review article

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SN - 2077-0383

VL - 13

JO - Journal of Clinical medicine

JF - Journal of Clinical medicine

IS - 11

M1 - 3020

ER -

Stereotactic Body Radiotherapy in Recurrent and Oligometastatic Head and Neck Tumours

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