Abstract
An important aspect of data quality when conducting clinical analyses using real-world data is how variables in the data have been recorded or measured. The discrepancy between an observed value and the true value is called measurement error (also known as noise in the artificial intelligence and machine learning literature) and can have consequences for your analyses in all kinds of contexts. To properly assess the potential impact of measurement error it is essential to understand the relationship between the true and observed variables as well as the goal of the analysis and how it will be implemented in practice. Commonly, measurement error is distinguished as being classical, Berkson, systematic and/or differential. While it is clear that measurement error can have far-reaching consequences on analyses, the effect can differ depending on whether analyses are descriptive, explanatory or predictive. Validation studies can inform the estimation and characterization of measurement error as well as provide crucial information for correction methods that are available in several statistical programming languages such as SAS, R and Python.
Original language | English |
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Title of host publication | Clinical Applications of Artificial Intelligence in Real-World Data |
Editors | Folkert W. Asselbergs, Spiros Denaxas, Daniel L. Oberski, Jason H. Moore |
Publisher | Springer |
Pages | 97-108 |
Number of pages | 12 |
Edition | 1 |
ISBN (Electronic) | 9783031366789 |
ISBN (Print) | 9783031366772 |
DOIs | |
Publication status | Published - 5 Nov 2023 |
Keywords
- Bias
- Correction
- Estimation
- Measurement error
- Misclassification
- Modelling
- Noise