TY - JOUR
T1 - Standardisation of nailfold capillaroscopy for the assessment of patients with Raynaud's phenomenon and systemic sclerosis
AU - Smith, Vanessa
AU - Herrick, Ariane L
AU - Ingegnoli, Francesca
AU - Damjanov, Nemanja
AU - De Angelis, Rossella
AU - Denton, Christopher P
AU - Distler, Oliver
AU - Espejo, Karinna
AU - Foeldvari, Ivan
AU - Frech, Tracy
AU - Garro, Boris
AU - Gutierrez, Marwin
AU - Gyger, Genevieve
AU - Hachulla, Eric
AU - Hesselstrand, Roger
AU - Iagnocco, Annamaria
AU - Kayser, Cristiane
AU - Melsens, Karin
AU - Müller-Ladner, Ulf
AU - Paolino, Sabrina
AU - Pizzorni, Carmen
AU - Radic, Mislav
AU - Riccieri, Valeria
AU - Snow, Marcus
AU - Stevens, Wendy
AU - Sulli, Alberto
AU - van Laar, Jacob M
AU - Vonk, Madelon C
AU - Vanhaecke, Amber
AU - Cutolo, Maurizio
N1 - Funding Information:
Ariane L. Herrick: Received research funding from Actelion and Gesynta, speaker's fees from Actelion, and consultancy fees from Boehringer-Ingelheim, Gesynta and Camurus.
Funding Information:
This work was supported by the NIHR Manchester Biomedical Research Centre.
Publisher Copyright:
© 2020 The Authors
PY - 2020/3
Y1 - 2020/3
N2 - Capillaroscopy is a non-invasive and safe tool which allows the evaluation of the morphology of the microcirculation. Since its recent incorporation in the 2013 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria for systemic sclerosis together with its assessed role to monitor disease progression, capillaroscopy became a 'mainstream' investigation for rheumatologists. Given its increasing use by a variety of physicians internationally both in daily practice to differentiate primary from secondary Raynaud's phenomenon, as well as in research context to predict disease progression and monitor treatment effects, standardisation in capillaroscopic image acquisition and analysis seems paramount. To step forward to this need, experts in the field of capillaroscopy/microcirculation provide in this very consensus paper their view on image acquisition and analysis, different capillaroscopic techniques, normal and abnormal capillaroscopic characteristics and their meaning, scoring systems and reliability of image acquisition and interpretation.
AB - Capillaroscopy is a non-invasive and safe tool which allows the evaluation of the morphology of the microcirculation. Since its recent incorporation in the 2013 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria for systemic sclerosis together with its assessed role to monitor disease progression, capillaroscopy became a 'mainstream' investigation for rheumatologists. Given its increasing use by a variety of physicians internationally both in daily practice to differentiate primary from secondary Raynaud's phenomenon, as well as in research context to predict disease progression and monitor treatment effects, standardisation in capillaroscopic image acquisition and analysis seems paramount. To step forward to this need, experts in the field of capillaroscopy/microcirculation provide in this very consensus paper their view on image acquisition and analysis, different capillaroscopic techniques, normal and abnormal capillaroscopic characteristics and their meaning, scoring systems and reliability of image acquisition and interpretation.
KW - Humans
KW - Microscopic Angioscopy
KW - Nails/blood supply
KW - Raynaud Disease/diagnosis
KW - Reproducibility of Results
KW - Scleroderma, Systemic/diagnosis
UR - http://www.scopus.com/inward/record.url?scp=85078946088&partnerID=8YFLogxK
U2 - 10.1016/j.autrev.2020.102458
DO - 10.1016/j.autrev.2020.102458
M3 - Review article
C2 - 31927087
SN - 1568-9972
VL - 19
SP - 1
EP - 14
JO - Autoimmunity Reviews
JF - Autoimmunity Reviews
IS - 3
M1 - 102458
ER -