Abstract
Chapter 2 explores the adaptive immune system, focusing on its essential components, mechanisms, and clinical implications. It describes the roles of T and B lymphocytes in antigen recognition, immune response activation, and the establishment of immunological memory, processes vital for effective pathogen elimination and long-term immunity. The chapter highlights the significance of antigen presentation, receptor diversity, and isotype switching in maintaining immune specificity and flexibility. Additionally, it explores the effects of adaptive immunity on transplantation, with particular attention to challenges such as graft rejection and alloimmunization, which significantly impact transplant success and patient outcomes. The chapter also briefly addresses the broader implications of adaptive immunity in transfusion medicine and other clinical applications. It emphasizes the critical role of advancing histocompatibility research and diagnostics to improve transplantation compatibility and immune management strategies.
| Original language | English |
|---|---|
| Title of host publication | Histocompatibility and Immunogenetics |
| Subtitle of host publication | A Guide for Practitioners |
| Publisher | Wiley |
| Pages | 39-67 |
| Number of pages | 29 |
| ISBN (Electronic) | 9783527847617 |
| ISBN (Print) | 9783527847600 |
| DOIs | |
| Publication status | Published - 1 Jan 2025 |