Specific cross-reactivity in sera from cystic echinococcosis patients in an enzyme-linked immunoelectrotransfer blot for cysticercosis diagnostics

H Rogier van Doorn*, Ellen Wentink-Bonnema, Rob J Rentenaar, Tom van Gool

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

A commercially available enzyme-linked immunoelectrotransfer blot originally intended for diagnosis of cysticercosis was evaluated for echinococcosis diagnosis, because a characteristic band pattern--different from the specific cysticercosis pattern--was observed in sera from patients with echinococcosis. This band pattern was observed in 29 (78%) of 37 parasitologically proven cystic echinococcosis patients. Specificity of these bands was 100% for echinococcosis, when tested with 75 control sera.

Original languageEnglish
Pages (from-to)948-950
Number of pages3
JournalTransactions of the Royal Society of Tropical Medicine and Hygiene
Volume101
Issue number9
DOIs
Publication statusPublished - Sept 2007
Externally publishedYes

Keywords

  • Antigens, Helminth/blood
  • Cross Reactions/immunology
  • Cysticercosis/diagnosis
  • Echinococcosis/diagnosis
  • Enzyme-Linked Immunosorbent Assay/methods
  • Humans

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