TY - JOUR
T1 - Similarities and controversies in imaging of pediatric renal tumors
T2 - A SIOP-RTSG and COG collaboration
AU - van der Beek, Justine N
AU - Artunduaga, Maddy
AU - Schenk, Jens-Peter
AU - Eklund, Meryle J
AU - Smith, Ethan A
AU - Lederman, Henrique M
AU - Warwick, Anne B
AU - Littooij, Annemieke S
AU - Khanna, Geetika
N1 - Funding Information:
We would like to acknowledge Drs. M. Verhagen from the University Medical Center Groningen (the Netherlands) for his permission to use the images made at their hospital.
Publisher Copyright:
© 2022 Wiley Periodicals LLC.
PY - 2023/5
Y1 - 2023/5
N2 - Malignant renal tumors are rare in children, and Wilms tumors (WTs) are the most common subtype. Imaging plays an essential role in the diagnosis, staging, and follow-up of these patients. Initial workup for staging is mainly performed by cross-sectional imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI). Imaging approach within the two core international groups, the Children's Oncology Group (COG, North America) and the International Society of Pediatric Oncology - Renal Tumor Study Group (SIOP-RTSG, Europe), differs. Whereas abdominal ultrasound (US) is used for the initial diagnosis of a suspected pediatric renal tumor globally, COG protocols support the use of CT or MRI for locoregional staging, contrary to the preference for MRI over CT for abdominopelvic evaluation within the SIOP-RTSG. The purpose of this manuscript is to summarize current imaging approaches, highlighting differences and similarities within these core international groups, while focusing on future innovative efforts and collaboration within the HARMONICA initiative.
AB - Malignant renal tumors are rare in children, and Wilms tumors (WTs) are the most common subtype. Imaging plays an essential role in the diagnosis, staging, and follow-up of these patients. Initial workup for staging is mainly performed by cross-sectional imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI). Imaging approach within the two core international groups, the Children's Oncology Group (COG, North America) and the International Society of Pediatric Oncology - Renal Tumor Study Group (SIOP-RTSG, Europe), differs. Whereas abdominal ultrasound (US) is used for the initial diagnosis of a suspected pediatric renal tumor globally, COG protocols support the use of CT or MRI for locoregional staging, contrary to the preference for MRI over CT for abdominopelvic evaluation within the SIOP-RTSG. The purpose of this manuscript is to summarize current imaging approaches, highlighting differences and similarities within these core international groups, while focusing on future innovative efforts and collaboration within the HARMONICA initiative.
KW - computed tomography
KW - kidney neoplasms
KW - magnetic resonance imaging
KW - pediatrics
KW - radiology
KW - ultrasonography
UR - http://www.scopus.com/inward/record.url?scp=85141563131&partnerID=8YFLogxK
U2 - 10.1002/pbc.30080
DO - 10.1002/pbc.30080
M3 - Review article
C2 - 36349564
SN - 1545-5009
VL - 70 Suppl 2
JO - Pediatric Blood & Cancer
JF - Pediatric Blood & Cancer
IS - S2
M1 - e30080
ER -