Short communication: prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa

W. van der Hoek; R. Sarge-Njie; T. Herremans; T. Chisnall; J. Okebe; E. Oriero; B. Versteeg; B. Goossens; M.A.B. van der Sande; B. Kampmann; D. Nwakanma

doi:10.1111/tmi.12116

Short communication: prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa

W. van der Hoek, R. Sarge-Njie, T. Herremans, T. Chisnall, J. Okebe, E. Oriero, B. Versteeg, B. Goossens, M.A.B. van der Sande, B. Kampmann, D. Nwakanma

Julius Center, dept. Epidemiology & Health Economics

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

OBJECTIVE: To estimate the prevalence of antibodies against Coxiella burnetii (Q fever) among children in eight villages in The Gambia, West Africa.

METHODS: Sera of 796 children aged 1-15 years were tested for presence of antibodies against phase II of C. burnetii by ELISA.

RESULTS: IgG and/or IgM phase II antibodies against C. burnetii were detectable in 8.3% (66/796) of all serum samples analysed with significant differences in seroprevalence between villages. Highest prevalence was found in the age group 1-4 years.

CONCLUSIONS: Exposure to C. burnetii is considerable in the early years of life in The Gambia, and further studies are warranted to estimate the role of Q fever in acute febrile illness in The Gambia and elsewhere in Africa.

Original language	English
Pages (from-to)	850-853
Number of pages	4
Journal	Tropical medicine & international health
Volume	18
Issue number	7
DOIs	https://doi.org/10.1111/tmi.12116
Publication status	Published - Jul 2013

Keywords

Adolescent
Age Factors
Antibodies
Antibodies, Bacterial
Child
Child, Preschool
Coxiella burnetii
Enzyme-Linked Immunosorbent Assay
Female
Gambia
Humans
Immunoglobulin G
Immunoglobulin M
Male
Q Fever
Seroepidemiologic Studies

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10.1111/tmi.12116

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van der Hoek, W., Sarge-Njie, R., Herremans, T., Chisnall, T., Okebe, J., Oriero, E., Versteeg, B., Goossens, B., van der Sande, M. A. B., Kampmann, B., & Nwakanma, D. (2013). Short communication: prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa. Tropical medicine & international health, 18(7), 850-853. https://doi.org/10.1111/tmi.12116

@article{47800af75a624f80907c12a1cdc78a43,

title = "Short communication: prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa",

abstract = "OBJECTIVE: To estimate the prevalence of antibodies against Coxiella burnetii (Q fever) among children in eight villages in The Gambia, West Africa.METHODS: Sera of 796 children aged 1-15 years were tested for presence of antibodies against phase II of C. burnetii by ELISA.RESULTS: IgG and/or IgM phase II antibodies against C. burnetii were detectable in 8.3% (66/796) of all serum samples analysed with significant differences in seroprevalence between villages. Highest prevalence was found in the age group 1-4 years.CONCLUSIONS: Exposure to C. burnetii is considerable in the early years of life in The Gambia, and further studies are warranted to estimate the role of Q fever in acute febrile illness in The Gambia and elsewhere in Africa.",

keywords = "Adolescent, Age Factors, Antibodies, Antibodies, Bacterial, Child, Child, Preschool, Coxiella burnetii, Enzyme-Linked Immunosorbent Assay, Female, Gambia, Humans, Immunoglobulin G, Immunoglobulin M, Male, Q Fever, Seroepidemiologic Studies",

author = "{van der Hoek}, W. and R. Sarge-Njie and T. Herremans and T. Chisnall and J. Okebe and E. Oriero and B. Versteeg and B. Goossens and {van der Sande}, M.A.B. and B. Kampmann and D. Nwakanma",

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year = "2013",

month = jul,

doi = "10.1111/tmi.12116",

language = "English",

volume = "18",

pages = "850--853",

journal = "Tropical medicine & international health",

issn = "1360-2276",

publisher = "Wiley-Blackwell",

number = "7",

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van der Hoek, W, Sarge-Njie, R, Herremans, T, Chisnall, T, Okebe, J, Oriero, E, Versteeg, B, Goossens, B, van der Sande, MAB, Kampmann, B & Nwakanma, D 2013, 'Short communication: prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa', Tropical medicine & international health, vol. 18, no. 7, pp. 850-853. https://doi.org/10.1111/tmi.12116

TY - JOUR

T1 - Short communication

T2 - prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa

AU - van der Hoek, W.

AU - Sarge-Njie, R.

AU - Herremans, T.

AU - Chisnall, T.

AU - Okebe, J.

AU - Oriero, E.

AU - Versteeg, B.

AU - Goossens, B.

AU - van der Sande, M.A.B.

AU - Kampmann, B.

AU - Nwakanma, D.

PY - 2013/7

Y1 - 2013/7

N2 - OBJECTIVE: To estimate the prevalence of antibodies against Coxiella burnetii (Q fever) among children in eight villages in The Gambia, West Africa.METHODS: Sera of 796 children aged 1-15 years were tested for presence of antibodies against phase II of C. burnetii by ELISA.RESULTS: IgG and/or IgM phase II antibodies against C. burnetii were detectable in 8.3% (66/796) of all serum samples analysed with significant differences in seroprevalence between villages. Highest prevalence was found in the age group 1-4 years.CONCLUSIONS: Exposure to C. burnetii is considerable in the early years of life in The Gambia, and further studies are warranted to estimate the role of Q fever in acute febrile illness in The Gambia and elsewhere in Africa.

AB - OBJECTIVE: To estimate the prevalence of antibodies against Coxiella burnetii (Q fever) among children in eight villages in The Gambia, West Africa.METHODS: Sera of 796 children aged 1-15 years were tested for presence of antibodies against phase II of C. burnetii by ELISA.RESULTS: IgG and/or IgM phase II antibodies against C. burnetii were detectable in 8.3% (66/796) of all serum samples analysed with significant differences in seroprevalence between villages. Highest prevalence was found in the age group 1-4 years.CONCLUSIONS: Exposure to C. burnetii is considerable in the early years of life in The Gambia, and further studies are warranted to estimate the role of Q fever in acute febrile illness in The Gambia and elsewhere in Africa.

KW - Adolescent

KW - Age Factors

KW - Antibodies

KW - Antibodies, Bacterial

KW - Child

KW - Child, Preschool

KW - Coxiella burnetii

KW - Enzyme-Linked Immunosorbent Assay

KW - Female

KW - Gambia

KW - Humans

KW - Immunoglobulin G

KW - Immunoglobulin M

KW - Male

KW - Q Fever

KW - Seroepidemiologic Studies

U2 - 10.1111/tmi.12116

DO - 10.1111/tmi.12116

M3 - Article

C2 - 23600611

SN - 1360-2276

VL - 18

SP - 850

EP - 853

JO - Tropical medicine & international health

JF - Tropical medicine & international health

IS - 7

ER -

Short communication: prevalence of antibodies against Coxiella burnetii (Q fever) in children in The Gambia, West Africa

Abstract

Keywords

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