Shaping national networks to improve patient access to advanced therapy medicinal products in Europe

Joyce M Hoek; Mike Broeders; Juan Francisco Hernandez; Heather Main; Pauline Meij; Daniël O Warmerdam; Lourens T Bloem; Renske M T ten Ham

doi:10.1016/j.drudis.2026.104661

Shaping national networks to improve patient access to advanced therapy medicinal products in Europe

Joyce M Hoek
, Mike Broeders
, Juan Francisco Hernandez
, Heather Main
, Pauline Meij
, Daniël O Warmerdam
, Lourens T Bloem
, Renske M T ten Ham^*
,

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

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Abstract

Advanced therapy medicinal products (ATMPs) offer the potential to address unmet medical needs, yet ensuring sustainable patient access remains challenging. In response, national ATMP networks are being established across Europe to strengthen ATMP development, cooperation between stakeholders and patient access. This targeted review provides an overview of (emerging) national ATMP networks across Europe and reflects on learnings and best practices. Drawing on insights from a Dutch multistakeholder workshop, a targeted European survey and interviews with established networks in the UK, Sweden and Ireland, this review concludes with recommendations to support the establishment of ATMP networks and improve patient access to ATMPs.

Original language	English
Article number	104661
Journal	Drug Discovery Today
Volume	31
Issue number	3
Early online date	3 Apr 2026
DOIs	https://doi.org/10.1016/j.drudis.2026.104661
Publication status	Published - May 2026

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10.1016/j.drudis.2026.104661Licence: CC BY

1-s2.0-S1359644626000668-main (1)Final published version, 790 KBLicence: CC BY

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title = "Shaping national networks to improve patient access to advanced therapy medicinal products in Europe",

abstract = "Advanced therapy medicinal products (ATMPs) offer the potential to address unmet medical needs, yet ensuring sustainable patient access remains challenging. In response, national ATMP networks are being established across Europe to strengthen ATMP development, cooperation between stakeholders and patient access. This targeted review provides an overview of (emerging) national ATMP networks across Europe and reflects on learnings and best practices. Drawing on insights from a Dutch multistakeholder workshop, a targeted European survey and interviews with established networks in the UK, Sweden and Ireland, this review concludes with recommendations to support the establishment of ATMP networks and improve patient access to ATMPs.",

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AU - Hoek, Joyce M

AU - Broeders, Mike

AU - Hernandez, Juan Francisco

AU - Main, Heather

AU - Meij, Pauline

AU - Warmerdam, Daniël O

AU - Bloem, Lourens T

AU - ten Ham, Renske M T

PY - 2026/5

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N2 - Advanced therapy medicinal products (ATMPs) offer the potential to address unmet medical needs, yet ensuring sustainable patient access remains challenging. In response, national ATMP networks are being established across Europe to strengthen ATMP development, cooperation between stakeholders and patient access. This targeted review provides an overview of (emerging) national ATMP networks across Europe and reflects on learnings and best practices. Drawing on insights from a Dutch multistakeholder workshop, a targeted European survey and interviews with established networks in the UK, Sweden and Ireland, this review concludes with recommendations to support the establishment of ATMP networks and improve patient access to ATMPs.

AB - Advanced therapy medicinal products (ATMPs) offer the potential to address unmet medical needs, yet ensuring sustainable patient access remains challenging. In response, national ATMP networks are being established across Europe to strengthen ATMP development, cooperation between stakeholders and patient access. This targeted review provides an overview of (emerging) national ATMP networks across Europe and reflects on learnings and best practices. Drawing on insights from a Dutch multistakeholder workshop, a targeted European survey and interviews with established networks in the UK, Sweden and Ireland, this review concludes with recommendations to support the establishment of ATMP networks and improve patient access to ATMPs.

UR - https://www.scopus.com/pages/publications/105040560494

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DO - 10.1016/j.drudis.2026.104661

M3 - Review article

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SN - 1359-6446

VL - 31

JO - Drug Discovery Today

JF - Drug Discovery Today

IS - 3

M1 - 104661

ER -

Shaping national networks to improve patient access to advanced therapy medicinal products in Europe

Abstract

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