Severe transient neonatal long QT syndrome due to maternal paroxetine usage: a case report

Eeke C M Leerssen; Ramon O Tak; Johannes M P J Breur

doi:10.1017/S1047951119001938

Severe transient neonatal long QT syndrome due to maternal paroxetine usage: a case report

Eeke C M Leerssen, Ramon O Tak, Johannes M P J Breur

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

A female neonate with in utero selective serotonin reuptake inhibitor exposure presented with bradycardia shortly after birth. Electrocardiography showed severe QT prolongation and second-degree atrioventricular block. Over time QT-times spontaneously normalised and genetic testing did not show mutations associated with long QT syndrome making maternal selective serotonin reuptake inhibitor usage the most likely explanation for the observed severe transient neonatal QT prolongation.

Original language	English
Pages (from-to)	1300-1301
Number of pages	2
Journal	Cardiology in the Young
Volume	29
Issue number	10
DOIs	https://doi.org/10.1017/S1047951119001938
Publication status	Published - Oct 2019

Keywords

Long QT syndrome
in utero exposure
neonate
paroxetine
selective serotonin reuptake inhibitor

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10.1017/S1047951119001938

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abstract = "A female neonate with in utero selective serotonin reuptake inhibitor exposure presented with bradycardia shortly after birth. Electrocardiography showed severe QT prolongation and second-degree atrioventricular block. Over time QT-times spontaneously normalised and genetic testing did not show mutations associated with long QT syndrome making maternal selective serotonin reuptake inhibitor usage the most likely explanation for the observed severe transient neonatal QT prolongation.",

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author = "Leerssen, {Eeke C M} and Tak, {Ramon O} and Breur, {Johannes M P J}",

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N2 - A female neonate with in utero selective serotonin reuptake inhibitor exposure presented with bradycardia shortly after birth. Electrocardiography showed severe QT prolongation and second-degree atrioventricular block. Over time QT-times spontaneously normalised and genetic testing did not show mutations associated with long QT syndrome making maternal selective serotonin reuptake inhibitor usage the most likely explanation for the observed severe transient neonatal QT prolongation.

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Severe transient neonatal long QT syndrome due to maternal paroxetine usage: a case report

Abstract

Keywords

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