TY - JOUR
T1 - Severe limb abnormalities
T2 - Analysis of a cluster of five cases born during a period of 45 days
AU - Van den Anker, J. N.
AU - Van Vught, E. E.
AU - Zandwijken, G. R.J.
AU - Cohen-Overbeek, T. E.
AU - Lindhout, D.
PY - 1993
Y1 - 1993
N2 - We report on 5 individuals with severe limb abnormalities born in our hospital within a period of 45 days. Detailed clinical descriptions, photographs, and radiographs are presented. Etiological evaluations included genetic background, obstetric history, invasive procedures during pregnancy, maternal infectious diseases or maternal hyperthermia, drug use before and during pregnancy, and occupational or recreational exposures of both parents.
AB - We report on 5 individuals with severe limb abnormalities born in our hospital within a period of 45 days. Detailed clinical descriptions, photographs, and radiographs are presented. Etiological evaluations included genetic background, obstetric history, invasive procedures during pregnancy, maternal infectious diseases or maternal hyperthermia, drug use before and during pregnancy, and occupational or recreational exposures of both parents.
KW - cocaine
KW - fetal drug exposure
KW - limb defects
KW - prenatal diagnosis
UR - http://www.scopus.com/inward/record.url?scp=0027526291&partnerID=8YFLogxK
U2 - 10.1002/ajmg.1320450528
DO - 10.1002/ajmg.1320450528
M3 - Article
C2 - 8456841
AN - SCOPUS:0027526291
SN - 0148-7299
VL - 45
SP - 659
EP - 667
JO - American Journal of Medical Genetics
JF - American Journal of Medical Genetics
IS - 5
ER -