TY - JOUR
T1 - Semen cryopreservation and usage rate for assisted reproductive technology in 898 men with cancer
AU - Muller, Iris
AU - Oude Ophuis, Ralph J A
AU - Broekmans, Frank J M
AU - Lock, Tycho M T W
PY - 2016/2
Y1 - 2016/2
N2 - An undesired side effect of cancer treatment is potential subfertility or infertility. Timely cryopreservation of semen is the best modality to ensure fertility. This retrospective data analysis established the usage rate of cryopreserved semen from cancer patients. Pubertal and post-pubertal patients who could become infertile as a result of cancer (treatment) were offered the option to cryopreserve semen prior to treatment. Of the 898 patients who cryopreserved their semen in our hospital, 96 (10.7%) used this for assisted reproductive technology. The live birth rates for intrauterine insemination, in-vitro fertilization, intracytoplasmic sperm injection and cryopreserved embryo transfer were 13%, 29%, 32% and 17%, respectively. Of all couples involved, 77% achieved parenthood, i.e. 60 of the 78 patients (with complete follow-up) fathered at least one child.
AB - An undesired side effect of cancer treatment is potential subfertility or infertility. Timely cryopreservation of semen is the best modality to ensure fertility. This retrospective data analysis established the usage rate of cryopreserved semen from cancer patients. Pubertal and post-pubertal patients who could become infertile as a result of cancer (treatment) were offered the option to cryopreserve semen prior to treatment. Of the 898 patients who cryopreserved their semen in our hospital, 96 (10.7%) used this for assisted reproductive technology. The live birth rates for intrauterine insemination, in-vitro fertilization, intracytoplasmic sperm injection and cryopreserved embryo transfer were 13%, 29%, 32% and 17%, respectively. Of all couples involved, 77% achieved parenthood, i.e. 60 of the 78 patients (with complete follow-up) fathered at least one child.
KW - Assisted reproductive technology
KW - Cancer
KW - Cryopreservation
KW - Semen
KW - Usage rate
UR - http://www.scopus.com/inward/record.url?scp=84949652637&partnerID=8YFLogxK
U2 - 10.1016/j.rbmo.2015.11.005
DO - 10.1016/j.rbmo.2015.11.005
M3 - Article
C2 - 26687904
AN - SCOPUS:84949652637
SN - 1472-6483
VL - 32
SP - 147
EP - 153
JO - Reproductive Biomedicine Online
JF - Reproductive Biomedicine Online
IS - 2
ER -