Semen cryopreservation and usage rate for assisted reproductive technology in 898 men with cancer

Iris Muller*, Ralph J A Oude Ophuis, Frank J M Broekmans, Tycho M T W Lock

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

An undesired side effect of cancer treatment is potential subfertility or infertility. Timely cryopreservation of semen is the best modality to ensure fertility. This retrospective data analysis established the usage rate of cryopreserved semen from cancer patients. Pubertal and post-pubertal patients who could become infertile as a result of cancer (treatment) were offered the option to cryopreserve semen prior to treatment. Of the 898 patients who cryopreserved their semen in our hospital, 96 (10.7%) used this for assisted reproductive technology. The live birth rates for intrauterine insemination, in-vitro fertilization, intracytoplasmic sperm injection and cryopreserved embryo transfer were 13%, 29%, 32% and 17%, respectively. Of all couples involved, 77% achieved parenthood, i.e. 60 of the 78 patients (with complete follow-up) fathered at least one child.

Original languageEnglish
Pages (from-to)147-153
Number of pages7
JournalReproductive Biomedicine Online
Volume32
Issue number2
DOIs
Publication statusPublished - Feb 2016

Keywords

  • Assisted reproductive technology
  • Cancer
  • Cryopreservation
  • Semen
  • Usage rate

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