Abstract
Dry mouth or xerostomia is the most frequently observed side-effect of radiotherapy (RT) in the head-and-neck region and is caused by salivary gland damage. The aim of this thesis was to determine the RT dose-response relationships for the parotid and submandibular glands and to investigate the effect of their sparing on patient-reported xerostomia after RT for tumors of the oropharynx.
The mean parotid gland dose can be used to estimate the risk of significant functional decline (flow reduction to
Original language | English |
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Qualification | Doctor of Philosophy |
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Award date | 28 Mar 2013 |
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Print ISBNs | 978-90-393-5927-3 |
Publication status | Published - 28 Mar 2013 |