Safety of routine early MRI in preterm infants

Annemarie Plaisier; Marlou M A Raets; Cynthia van der Starre; Monique Feijen-Roon; Paul Govaert; Maarten H Lequin; Anneriet M Heemskerk; Jeroen Dudink

doi:10.1007/s00247-012-2426-y

Safety of routine early MRI in preterm infants

Annemarie Plaisier, Marlou M A Raets, Cynthia van der Starre, Monique Feijen-Roon, Paul Govaert, Maarten H Lequin, Anneriet M Heemskerk, Jeroen Dudink

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

BACKGROUND: Cerebral MRI performed on preterm infants at term-equivalent 30 weeks' gestational age (GA) is increasingly performed as part of standard clinical care.

OBJECTIVE: We evaluated safety of these early MRI procedures.

MATERIALS AND METHODS: We retrospectively collected data on patient safety of preterm infants who underwent early MRI scans. Data were collected at fixed times before and after the MRI scan. MRI procedures were carried out according to a comprehensive guideline.

RESULTS: A total of 52 infants underwent an MRI scan at 30 weeks' GA. Although no serious adverse events occurred and vital parameters remained stable during the procedure, minor adverse events were encountered in 26 infants (50%). The MRI was terminated in three infants (5.8%) because of respiratory instability. Increased respiratory support within 24 h after the MRI was necessary for 12 infants (23.1%) and was significantly associated with GA, birth weight and the mode of respiratory support. Hypothermia (core temperature < 36°C) occurred in nine infants (17.3%). Temperature dropped significantly after the MRI scan.

CONCLUSION: Minor adverse events after MRI procedures at 30 weeks GA were common and should not be underestimated. A dedicated and comprehensive guideline for MRI procedures in preterm infants is essential.

Original language	English
Pages (from-to)	1205-11
Number of pages	7
Journal	Pediatric Radiology
Volume	42
Issue number	10
DOIs	https://doi.org/10.1007/s00247-012-2426-y
Publication status	Published - 2012

Keywords

Female
Humans
Hypothermia
Incidence
Infant, Newborn
Infant, Premature
Infant, Very Low Birth Weight
Magnetic Resonance Imaging
Netherlands
Respiration Disorders
Risk Factors

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10.1007/s00247-012-2426-y

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title = "Safety of routine early MRI in preterm infants",

abstract = "BACKGROUND: Cerebral MRI performed on preterm infants at term-equivalent 30 weeks' gestational age (GA) is increasingly performed as part of standard clinical care.OBJECTIVE: We evaluated safety of these early MRI procedures.MATERIALS AND METHODS: We retrospectively collected data on patient safety of preterm infants who underwent early MRI scans. Data were collected at fixed times before and after the MRI scan. MRI procedures were carried out according to a comprehensive guideline.RESULTS: A total of 52 infants underwent an MRI scan at 30 weeks' GA. Although no serious adverse events occurred and vital parameters remained stable during the procedure, minor adverse events were encountered in 26 infants (50%). The MRI was terminated in three infants (5.8%) because of respiratory instability. Increased respiratory support within 24 h after the MRI was necessary for 12 infants (23.1%) and was significantly associated with GA, birth weight and the mode of respiratory support. Hypothermia (core temperature < 36°C) occurred in nine infants (17.3%). Temperature dropped significantly after the MRI scan.CONCLUSION: Minor adverse events after MRI procedures at 30 weeks GA were common and should not be underestimated. A dedicated and comprehensive guideline for MRI procedures in preterm infants is essential.",

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author = "Annemarie Plaisier and Raets, {Marlou M A} and {van der Starre}, Cynthia and Monique Feijen-Roon and Paul Govaert and Lequin, {Maarten H} and Heemskerk, {Anneriet M} and Jeroen Dudink",

year = "2012",

doi = "10.1007/s00247-012-2426-y",

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AU - Plaisier, Annemarie

AU - Raets, Marlou M A

AU - van der Starre, Cynthia

AU - Feijen-Roon, Monique

AU - Govaert, Paul

AU - Lequin, Maarten H

AU - Heemskerk, Anneriet M

AU - Dudink, Jeroen

PY - 2012

Y1 - 2012

N2 - BACKGROUND: Cerebral MRI performed on preterm infants at term-equivalent 30 weeks' gestational age (GA) is increasingly performed as part of standard clinical care.OBJECTIVE: We evaluated safety of these early MRI procedures.MATERIALS AND METHODS: We retrospectively collected data on patient safety of preterm infants who underwent early MRI scans. Data were collected at fixed times before and after the MRI scan. MRI procedures were carried out according to a comprehensive guideline.RESULTS: A total of 52 infants underwent an MRI scan at 30 weeks' GA. Although no serious adverse events occurred and vital parameters remained stable during the procedure, minor adverse events were encountered in 26 infants (50%). The MRI was terminated in three infants (5.8%) because of respiratory instability. Increased respiratory support within 24 h after the MRI was necessary for 12 infants (23.1%) and was significantly associated with GA, birth weight and the mode of respiratory support. Hypothermia (core temperature < 36°C) occurred in nine infants (17.3%). Temperature dropped significantly after the MRI scan.CONCLUSION: Minor adverse events after MRI procedures at 30 weeks GA were common and should not be underestimated. A dedicated and comprehensive guideline for MRI procedures in preterm infants is essential.

AB - BACKGROUND: Cerebral MRI performed on preterm infants at term-equivalent 30 weeks' gestational age (GA) is increasingly performed as part of standard clinical care.OBJECTIVE: We evaluated safety of these early MRI procedures.MATERIALS AND METHODS: We retrospectively collected data on patient safety of preterm infants who underwent early MRI scans. Data were collected at fixed times before and after the MRI scan. MRI procedures were carried out according to a comprehensive guideline.RESULTS: A total of 52 infants underwent an MRI scan at 30 weeks' GA. Although no serious adverse events occurred and vital parameters remained stable during the procedure, minor adverse events were encountered in 26 infants (50%). The MRI was terminated in three infants (5.8%) because of respiratory instability. Increased respiratory support within 24 h after the MRI was necessary for 12 infants (23.1%) and was significantly associated with GA, birth weight and the mode of respiratory support. Hypothermia (core temperature < 36°C) occurred in nine infants (17.3%). Temperature dropped significantly after the MRI scan.CONCLUSION: Minor adverse events after MRI procedures at 30 weeks GA were common and should not be underestimated. A dedicated and comprehensive guideline for MRI procedures in preterm infants is essential.

KW - Female

KW - Humans

KW - Hypothermia

KW - Incidence

KW - Infant, Newborn

KW - Infant, Premature

KW - Infant, Very Low Birth Weight

KW - Magnetic Resonance Imaging

KW - Netherlands

KW - Respiration Disorders

KW - Risk Factors

U2 - 10.1007/s00247-012-2426-y

DO - 10.1007/s00247-012-2426-y

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SN - 0301-0449

VL - 42

SP - 1205

EP - 1211

JO - Pediatric Radiology

JF - Pediatric Radiology

IS - 10

ER -

Safety of routine early MRI in preterm infants

Abstract

Keywords

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