Abstract
Correct differentiation between tumor masses and healthy edematous brain tissue is essential for successful surgical treatment of a malignant glioma. Unfortunately, without suitable imaging methods (intraoperative USG, CT or MRI), it is often impossible even for an experienced surgeon to determine the tumor edges. The author has presented the possibilities of using exogenous fluorophores (delta-aminolevulinic acid, protoporphyrins, fluorescein, etc.) and autofluorescence for peroperative visualization and delineation of tumor masses and normal brain tissue as a hopeful alternative to conventionally used intraoperative imaging methods.
| Translated title of the contribution | Current possibilities of per-operative visualization of malignant gliomas using fluorescent methods |
|---|---|
| Original language | Slovak |
| Pages (from-to) | 426-430 |
| Number of pages | 5 |
| Journal | Ceska a Slovenska Neurologie a Neurochirurgie |
| Volume | 69 |
| Issue number | 6 |
| Publication status | Published - 2006 |
| Externally published | Yes |
Keywords
- Delta-aminolevulinic acid
- Fluorescein
- Fluorescence
- Malignant glioma
- Protoporphyrin