Roles of LIM kinases in central nervous system function and dysfunction

H. Cuberos; B. Vallée; Patrick Vourc'h; J. Tastet; Christian R Andres; H. Bénédetti

doi:10.1016/j.febslet.2015.10.032

Roles of LIM kinases in central nervous system function and dysfunction

H. Cuberos^*, B. Vallée, Patrick Vourc'h, J. Tastet, Christian R Andres, H. Bénédetti

^*Corresponding author for this work

Translational Neuroscience

Research output: Contribution to journal › Review article › peer-review

6 Citations (Scopus)

Abstract

We finally present the existence of a cofilin-independent pathway also involved in neuronal function. A better understanding of the differences between both LIMKs and of the precise molecular mechanisms involved in their mode of action and regulation is now required to improve our understanding of the physiopathology of the neuronal diseases associated with LIMKs.

Original language	English
Pages (from-to)	3795-3806
Number of pages	12
Journal	FEBS letters
Volume	589
Issue number	24
DOIs	https://doi.org/10.1016/j.febslet.2015.10.032
Publication status	Published - 21 Dec 2015

Keywords

LIM kinase 1
LIM kinase 2
Neurodegenerative disease
Neurodevelopmental disease
Neuronal function

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10.1016/j.febslet.2015.10.032

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title = "Roles of LIM kinases in central nervous system function and dysfunction",

abstract = "We finally present the existence of a cofilin-independent pathway also involved in neuronal function. A better understanding of the differences between both LIMKs and of the precise molecular mechanisms involved in their mode of action and regulation is now required to improve our understanding of the physiopathology of the neuronal diseases associated with LIMKs.",

keywords = "LIM kinase 1, LIM kinase 2, Neurodegenerative disease, Neurodevelopmental disease, Neuronal function",

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AU - Cuberos, H.

AU - Vallée, B.

AU - Vourc'h, Patrick

AU - Tastet, J.

AU - Andres, Christian R

AU - Bénédetti, H.

PY - 2015/12/21

Y1 - 2015/12/21

N2 - We finally present the existence of a cofilin-independent pathway also involved in neuronal function. A better understanding of the differences between both LIMKs and of the precise molecular mechanisms involved in their mode of action and regulation is now required to improve our understanding of the physiopathology of the neuronal diseases associated with LIMKs.

AB - We finally present the existence of a cofilin-independent pathway also involved in neuronal function. A better understanding of the differences between both LIMKs and of the precise molecular mechanisms involved in their mode of action and regulation is now required to improve our understanding of the physiopathology of the neuronal diseases associated with LIMKs.

KW - LIM kinase 1

KW - LIM kinase 2

KW - Neurodegenerative disease

KW - Neurodevelopmental disease

KW - Neuronal function

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DO - 10.1016/j.febslet.2015.10.032

M3 - Review article

C2 - 26545494

AN - SCOPUS:84959560233

SN - 0014-5793

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JO - FEBS letters

JF - FEBS letters

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ER -

Roles of LIM kinases in central nervous system function and dysfunction

Abstract

Keywords

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