TY - JOUR
T1 - Robot-assisted spleen preserving pancreatic surgery in MEN1 patients
AU - Nell, Sjoerd
AU - Brunaud, Laurent
AU - Ayav, Ahmet
AU - Bonsing, Bert A.
AU - Groot Koerkamp, Bas
AU - Nieveen van Dijkum, Els J.
AU - Kazemier, Geert
AU - de Kleine, Ruben H J
AU - Hagendoorn, Jeroen
AU - Molenaar, I. Quintus
AU - Valk, Gerlof D.
AU - Borel Rinkes, Inne H M
AU - Vriens, Menno R.
PY - 2016/9/15
Y1 - 2016/9/15
N2 - Background: Multiple Endocrine Neoplasia type 1 (MEN1) patients often undergo multiple pancreatic operations at a young age. Objective: To describe robot-assisted and laparoscopic spleen-preserving pancreatic surgery in MEN1 patients, and to compare both techniques. Methods: Robot-assisted pancreatectomies of the DutchMEN1 study group and the Université de Lorraine, Nancy, France were compared to a historical cohort of laparoscopic treated MEN1 patients. Perioperative outcomes were compared. Results: A total of 21 MEN1 patients underwent minimally invasive pancreatic surgery for pancreatic neuroendocrine tumors, seven patients were subjected to robot-assisted surgery, and 14 patients underwent laparoscopic surgery. Demographics and clinical characteristics did not differ between the cohorts and no significant differences in operative outcomes were found. A high number of ISGPS grade B/C pancreatic fistulas were observed in both cohorts (38%), and no conversions were seen in the robot-assisted cohort (respectively 0% vs. 43%, P = 0.06). In one laparoscopic and one robot-assisted case the primary tumor was not resected. Conclusions: Minimally invasive spleen-preserving surgery in MEN1 patients is safe and feasible. Patients who underwent robot-assisted surgery did not require conversion to open surgery.
AB - Background: Multiple Endocrine Neoplasia type 1 (MEN1) patients often undergo multiple pancreatic operations at a young age. Objective: To describe robot-assisted and laparoscopic spleen-preserving pancreatic surgery in MEN1 patients, and to compare both techniques. Methods: Robot-assisted pancreatectomies of the DutchMEN1 study group and the Université de Lorraine, Nancy, France were compared to a historical cohort of laparoscopic treated MEN1 patients. Perioperative outcomes were compared. Results: A total of 21 MEN1 patients underwent minimally invasive pancreatic surgery for pancreatic neuroendocrine tumors, seven patients were subjected to robot-assisted surgery, and 14 patients underwent laparoscopic surgery. Demographics and clinical characteristics did not differ between the cohorts and no significant differences in operative outcomes were found. A high number of ISGPS grade B/C pancreatic fistulas were observed in both cohorts (38%), and no conversions were seen in the robot-assisted cohort (respectively 0% vs. 43%, P = 0.06). In one laparoscopic and one robot-assisted case the primary tumor was not resected. Conclusions: Minimally invasive spleen-preserving surgery in MEN1 patients is safe and feasible. Patients who underwent robot-assisted surgery did not require conversion to open surgery.
KW - laparoscopic pancreatic surgery
KW - multiple endocrine neoplasia type 1
KW - neuroendocrine tumors
KW - pancreas
KW - robot-assisted pancreatic surgery
UR - http://www.scopus.com/inward/record.url?scp=84990214566&partnerID=8YFLogxK
U2 - 10.1002/jso.24315
DO - 10.1002/jso.24315
M3 - Article
C2 - 27263513
AN - SCOPUS:84990214566
SN - 0022-4790
VL - 114
SP - 456
EP - 461
JO - Journal of Surgical Oncology
JF - Journal of Surgical Oncology
IS - 4
ER -