Risk of bilateral visual impairment in individuals with amblyopia: the Rotterdam study

Redmer van Leeuwen; Marinus J C Eijkemans; Johannes R Vingerling; Albert Hofman; Paulus T V M de Jong; Huib J Simonsz

doi:10.1136/bjo.2006.113670

Risk of bilateral visual impairment in individuals with amblyopia: the Rotterdam study

Redmer van Leeuwen
, Marinus J C Eijkemans
, Johannes R Vingerling
, Albert Hofman
, Paulus T V M de Jong
, Huib J Simonsz

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

BACKGROUND: The excess risk of bilateral visual impairment (BVI; bilateral visual acuity <0.5) among individuals with amblyopia is an argument for screening for amblyopia, but data are scarce.

METHODS: The risk was estimated by determining the incidence of BVI in the Rotterdam Study, a population-based cohort of subjects aged 55 years or over (n = 5220), including 192 individuals with amblyopia (3.7%). Using a multistate lifetable, the lifetime risk and excess period spent with BVI were determined.

RESULTS: The relative risk of BVI for amblyopes was 2.6 (95% confidence interval 1.4-4.5). For individuals with amblyopia, the lifetime risk of BVI was 18%, whereas they lived on average 7.2 years with BVI. For non-amblyopic individuals, these figures were 10% and 6.7 years, respectively.

CONCLUSION: Amblyopia nearly doubles the lifetime risk of BVI and affected individuals spent an extra six months with BVI. This study provides data for future cost-effectiveness analyses.

Original language	English
Pages (from-to)	1450-1
Number of pages	2
Journal	British Journal of Ophthalmology
Volume	91
Issue number	11
DOIs	https://doi.org/10.1136/bjo.2006.113670
Publication status	Published - Nov 2007

Keywords

Age Factors
Aged
Aged, 80 and over
Amblyopia
Epidemiologic Methods
Female
Humans
Male
Middle Aged
Netherlands
Time Factors
Vision, Low
Visual Acuity
Journal Article

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10.1136/bjo.2006.113670

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@article{fe7dc90db10b4ab3b3391c65baa7c695,

title = "Risk of bilateral visual impairment in individuals with amblyopia: the Rotterdam study",

abstract = "BACKGROUND: The excess risk of bilateral visual impairment (BVI; bilateral visual acuity <0.5) among individuals with amblyopia is an argument for screening for amblyopia, but data are scarce.METHODS: The risk was estimated by determining the incidence of BVI in the Rotterdam Study, a population-based cohort of subjects aged 55 years or over (n = 5220), including 192 individuals with amblyopia (3.7\%). Using a multistate lifetable, the lifetime risk and excess period spent with BVI were determined.RESULTS: The relative risk of BVI for amblyopes was 2.6 (95\% confidence interval 1.4-4.5). For individuals with amblyopia, the lifetime risk of BVI was 18\%, whereas they lived on average 7.2 years with BVI. For non-amblyopic individuals, these figures were 10\% and 6.7 years, respectively.CONCLUSION: Amblyopia nearly doubles the lifetime risk of BVI and affected individuals spent an extra six months with BVI. This study provides data for future cost-effectiveness analyses.",

keywords = "Age Factors, Aged, Aged, 80 and over, Amblyopia, Epidemiologic Methods, Female, Humans, Male, Middle Aged, Netherlands, Time Factors, Vision, Low, Visual Acuity, Journal Article",

author = "\{van Leeuwen\}, Redmer and Eijkemans, \{Marinus J C\} and Vingerling, \{Johannes R\} and Albert Hofman and \{de Jong\}, \{Paulus T V M\} and Simonsz, \{Huib J\}",

year = "2007",

month = nov,

doi = "10.1136/bjo.2006.113670",

language = "English",

volume = "91",

pages = "1450--1",

journal = "British Journal of Ophthalmology",

issn = "0007-1161",

publisher = "BMJ Publishing Group",

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T1 - Risk of bilateral visual impairment in individuals with amblyopia

T2 - the Rotterdam study

AU - van Leeuwen, Redmer

AU - Eijkemans, Marinus J C

AU - Vingerling, Johannes R

AU - Hofman, Albert

AU - de Jong, Paulus T V M

AU - Simonsz, Huib J

PY - 2007/11

Y1 - 2007/11

N2 - BACKGROUND: The excess risk of bilateral visual impairment (BVI; bilateral visual acuity <0.5) among individuals with amblyopia is an argument for screening for amblyopia, but data are scarce.METHODS: The risk was estimated by determining the incidence of BVI in the Rotterdam Study, a population-based cohort of subjects aged 55 years or over (n = 5220), including 192 individuals with amblyopia (3.7%). Using a multistate lifetable, the lifetime risk and excess period spent with BVI were determined.RESULTS: The relative risk of BVI for amblyopes was 2.6 (95% confidence interval 1.4-4.5). For individuals with amblyopia, the lifetime risk of BVI was 18%, whereas they lived on average 7.2 years with BVI. For non-amblyopic individuals, these figures were 10% and 6.7 years, respectively.CONCLUSION: Amblyopia nearly doubles the lifetime risk of BVI and affected individuals spent an extra six months with BVI. This study provides data for future cost-effectiveness analyses.

AB - BACKGROUND: The excess risk of bilateral visual impairment (BVI; bilateral visual acuity <0.5) among individuals with amblyopia is an argument for screening for amblyopia, but data are scarce.METHODS: The risk was estimated by determining the incidence of BVI in the Rotterdam Study, a population-based cohort of subjects aged 55 years or over (n = 5220), including 192 individuals with amblyopia (3.7%). Using a multistate lifetable, the lifetime risk and excess period spent with BVI were determined.RESULTS: The relative risk of BVI for amblyopes was 2.6 (95% confidence interval 1.4-4.5). For individuals with amblyopia, the lifetime risk of BVI was 18%, whereas they lived on average 7.2 years with BVI. For non-amblyopic individuals, these figures were 10% and 6.7 years, respectively.CONCLUSION: Amblyopia nearly doubles the lifetime risk of BVI and affected individuals spent an extra six months with BVI. This study provides data for future cost-effectiveness analyses.

KW - Age Factors

KW - Aged

KW - Aged, 80 and over

KW - Amblyopia

KW - Epidemiologic Methods

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Netherlands

KW - Time Factors

KW - Vision, Low

KW - Visual Acuity

KW - Journal Article

U2 - 10.1136/bjo.2006.113670

DO - 10.1136/bjo.2006.113670

M3 - Article

C2 - 17522151

SN - 0007-1161

VL - 91

SP - 1450

EP - 1451

JO - British Journal of Ophthalmology

JF - British Journal of Ophthalmology

IS - 11

ER -

Risk of bilateral visual impairment in individuals with amblyopia: the Rotterdam study

Abstract

Keywords

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