Risk factors and diagnostic strategies in colorectal cancer

A.M. Leufkens

Risk factors and diagnostic strategies in colorectal cancer

A.M. Leufkens

Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

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Abstract

Colorectal cancer (CRC) is a major public health problem. The goal of this thesis was to investigate factors that influence the risk of developing CRC and to examine the clinical value of various diagnostic procedures to investigate the large bowel. Screening for adenomas is an effective way to reduce mortality from CRC. A significant number of polyps is missed during routine colonoscopy. The Third Eye Retroscope, abbreviated as Third Eye, provides an additional, retrograde view that is able to detect polyps behind folds and curves in the colon. In this thesis, we report that the risk of missing a lesion during colonoscopy without the Third Eye compared to colonoscopy with the Third Eye was more than 2.5 times higher for polyps (p

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	Utrecht University
Supervisors/Advisors	Siersema, PD, Primary supervisor Bueno de Mesquita, HB, Co-supervisor van Duijnhoven, F.J.B, Co-supervisor, External person
Award date	31 May 2011
Publisher	Utrecht University
Print ISBNs	978-90-393-5536-7
Publication status	Published - 31 May 2011

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title = "Risk factors and diagnostic strategies in colorectal cancer",

abstract = "Colorectal cancer (CRC) is a major public health problem. The goal of this thesis was to investigate factors that influence the risk of developing CRC and to examine the clinical value of various diagnostic procedures to investigate the large bowel. Screening for adenomas is an effective way to reduce mortality from CRC. A significant number of polyps is missed during routine colonoscopy. The Third Eye Retroscope, abbreviated as Third Eye, provides an additional, retrograde view that is able to detect polyps behind folds and curves in the colon. In this thesis, we report that the risk of missing a lesion during colonoscopy without the Third Eye compared to colonoscopy with the Third Eye was more than 2.5 times higher for polyps (p",

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AB - Colorectal cancer (CRC) is a major public health problem. The goal of this thesis was to investigate factors that influence the risk of developing CRC and to examine the clinical value of various diagnostic procedures to investigate the large bowel. Screening for adenomas is an effective way to reduce mortality from CRC. A significant number of polyps is missed during routine colonoscopy. The Third Eye Retroscope, abbreviated as Third Eye, provides an additional, retrograde view that is able to detect polyps behind folds and curves in the colon. In this thesis, we report that the risk of missing a lesion during colonoscopy without the Third Eye compared to colonoscopy with the Third Eye was more than 2.5 times higher for polyps (p

M3 - Doctoral thesis 1 (Research UU / Graduation UU)

SN - 978-90-393-5536-7

PB - Utrecht University

ER -

Risk factors and diagnostic strategies in colorectal cancer

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