Repetitive Immune-Mediated Noninfectious Endocarditis Necessitating 5 Mitral Valve Replacements

Steven A. Muller*, Helen L. Leavis, Karim Taha, Leo Koenderman, Steven A.J. Chamuleau, Willem J.L. Suyker, Maarten J. Cramer

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

We present a young patient who had to undergo 5 mitral valve replacements (MVR) because of a repetitive immune-mediated noninfectious endocarditis. The patient was treated with multiple anti-inflammatory drugs and high-dose prednisone. After the fifth MVR, the patient remained in stable condition using Anakinra after 22 months of follow-up. (Level of Difficulty: Advanced.).

Original languageEnglish
Pages (from-to)1483-1488
Number of pages6
JournalJACC Case Rep
Volume3
Issue number13
DOIs
Publication statusPublished - 6 Oct 2021

Keywords

  • Anakinra
  • autoimmune
  • endocarditis
  • mitral valve replacement
  • repetitive

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