Renal transplant patient survives a donor-derived abdominal invasive mucormycosis (Lichtheimia ramosa)

E M Spithoven, A H W Bruns, B J Petri, P J Haas, T Q Nguyen, F Hagen, A D van Zuilen

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Abstract

Mucormycosis is a life-threatening invasive fungal infection, most commonly described in severely immunocompromised patients. It is characterized by rapid invasive growth of the fungus and often with fatal outcome. We report a case of a renal transplant recipient diagnosed with a donor-derived invasive mucormycosis. In this patient, we used a step-wise approach of withdrawal of immunosuppressants, antifungal induction therapy, extensive surgical debridement of all (potentially) infected tissue, abdominal irrigation of liposomal amphotericin B and interferon gamma. Due to rapid diagnosis and intensive therapy the patient survived.

Original languageEnglish
Pages (from-to)39-42
Number of pages4
JournalMedical Mycology Case Reports
Volume30
DOIs
Publication statusPublished - Dec 2020

Keywords

  • Interferon gamma
  • mucormycosis
  • Renal transplant
  • Survival

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