Renal failure associated with the use of dextran-40

J. H. Zwaveling; J. Meulenbelt; N. H W van Xanten; R. J. Hené

Renal failure associated with the use of dextran-40

J. H. Zwaveling^*, J. Meulenbelt, N. H W van Xanten, R. J. Hené

^*Corresponding author for this work

Clinical Toxicology

Research output: Contribution to journal › Article › Academic › peer-review

13 Citations (Scopus)

Abstract

A typical case of dextran-40 associated acute renal failure is presented. In this patient a single plasma exchange was successful in considerably lowering the plasma dextran concentration. At the same time the elevated plasma oncotic pressure was reduced to normal values. Diuresis returned within 12 h. Several possible explanations of the mechanism of renal failure assocociated with the use of dextran-40 are discussed. While the mechanism of dextran-associated renal failure remains unsolved, plasma exchange seems to be effective therapy.

Original language	English
Pages (from-to)	321-326
Number of pages	6
Journal	Netherlands Journal of Medicine
Volume	35
Issue number	6
Publication status	Published - 1 Dec 1989

Keywords

Dextran-40
Plasma exchange
Renal failure

Cite this

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title = "Renal failure associated with the use of dextran-40",

abstract = "A typical case of dextran-40 associated acute renal failure is presented. In this patient a single plasma exchange was successful in considerably lowering the plasma dextran concentration. At the same time the elevated plasma oncotic pressure was reduced to normal values. Diuresis returned within 12 h. Several possible explanations of the mechanism of renal failure assocociated with the use of dextran-40 are discussed. While the mechanism of dextran-associated renal failure remains unsolved, plasma exchange seems to be effective therapy.",

keywords = "Dextran-40, Plasma exchange, Renal failure",

author = "Zwaveling, {J. H.} and J. Meulenbelt and {van Xanten}, {N. H W} and Hen{\'e}, {R. J.}",

year = "1989",

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TY - JOUR

T1 - Renal failure associated with the use of dextran-40

AU - Zwaveling, J. H.

AU - Meulenbelt, J.

AU - van Xanten, N. H W

AU - Hené, R. J.

PY - 1989/12/1

Y1 - 1989/12/1

N2 - A typical case of dextran-40 associated acute renal failure is presented. In this patient a single plasma exchange was successful in considerably lowering the plasma dextran concentration. At the same time the elevated plasma oncotic pressure was reduced to normal values. Diuresis returned within 12 h. Several possible explanations of the mechanism of renal failure assocociated with the use of dextran-40 are discussed. While the mechanism of dextran-associated renal failure remains unsolved, plasma exchange seems to be effective therapy.

AB - A typical case of dextran-40 associated acute renal failure is presented. In this patient a single plasma exchange was successful in considerably lowering the plasma dextran concentration. At the same time the elevated plasma oncotic pressure was reduced to normal values. Diuresis returned within 12 h. Several possible explanations of the mechanism of renal failure assocociated with the use of dextran-40 are discussed. While the mechanism of dextran-associated renal failure remains unsolved, plasma exchange seems to be effective therapy.

KW - Dextran-40

KW - Plasma exchange

KW - Renal failure

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M3 - Article

C2 - 2483959

AN - SCOPUS:0024811770

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VL - 35

SP - 321

EP - 326

JO - Netherlands Journal of Medicine

JF - Netherlands Journal of Medicine

IS - 6

ER -

Renal failure associated with the use of dextran-40

Abstract

Keywords

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