Region based perfusion estimation in peripherals using C-arm systems: A simulation study

Marco Giordano*, Evert Jan Vonken, Matthias Bertram, Willem Mali, Max A. Viergever, Christoph Neukirchen

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

1 Citation (Scopus)

Abstract

In this paper we evaluate a method for region based perfusion estimation in peripherals using angiographic C-arm systems. The method is based on X-ray angiography acquired from a fixed viewing position and on a segmentation of the object in regions derived from two rotational soft tissue scans. The 2D blood flow information contained in the angiography is mapped to the 3D segmented regions by optimization of an inverse problem providing region averaged quantitative perfusion. The accuracy of the method is assessed in a simulation study using a CT perfusion acquisition as input data. Results show that the method is suitable for average perfusion estimation, however when trying to resolve finer perfused structures by increasing the number of segmented regions, higher estimation errors are introduced in solving the inverse problem.

Original languageEnglish
Title of host publication2011 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011
Pages2918-2921
Number of pages4
DOIs
Publication statusPublished - 26 Mar 2012
Event2011 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011 - Valencia, Spain
Duration: 23 Oct 201129 Oct 2011

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863

Conference

Conference2011 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011
Country/TerritorySpain
CityValencia
Period23/10/1129/10/11

Keywords

  • C-arm
  • Perfusion imaging
  • peripheral arterial disease
  • temporal attenuation curves
  • X-ray angiography

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