Recent Advances in Pancreatic Cancer Surgery of Relevance to the Practicing Pathologist

Lennart B van Rijssen; Steffi J E Rombouts; Marieke S Walma; Jantien A Vogel; Johanna A Tol; IQ Molenaar; Casper H J van Eijck; Joanne Verheij; Marc J van de Vijver; Olivier R C Busch; Marc G H Besselink

doi:10.1016/j.path.2016.05.002

Recent Advances in Pancreatic Cancer Surgery of Relevance to the Practicing Pathologist

Lennart B van Rijssen
, Steffi J E Rombouts
, Marieke S Walma
, Jantien A Vogel
, Johanna A Tol
, IQ Molenaar
, Casper H J van Eijck
, Joanne Verheij
, Marc J van de Vijver
, Olivier R C Busch
, Marc G H Besselink
,

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Recent advances in pancreatic surgery have the potential to improve outcomes for patients with pancreatic cancer. We address 3 new, trending topics in pancreatic surgery that are of relevance to the pathologist. First, increasing awareness of the prognostic impact of intraoperatively detected extraregional and regional lymph node metastases and the international consensus definition on lymph node sampling and reporting. Second, neoadjuvant chemotherapy, which is capable of changing 10% to 20% of initially unresectable, to resectable disease. Third, in patients who remain unresectable following neoadjuvant chemotherapy, local ablative therapies may change indications for treatment and improve outcomes.

Original language	English
Pages (from-to)	539-545
Number of pages	7
Journal	Surgical Pathology Clinics
Volume	9
Issue number	4
DOIs	https://doi.org/10.1016/j.path.2016.05.002
Publication status	Published - Dec 2016

Keywords

Whipple
Pancreatoduodenectomy
Pancreas
Surgery
Pathology
Lymph node
Neoadjuvant
Radiofrequency ablation

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10.1016/j.path.2016.05.002

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van Rijssen, L. B., Rombouts, S. J. E., Walma, M. S., Vogel, J. A., Tol, J. A., Molenaar, IQ., van Eijck, C. H. J., Verheij, J., van de Vijver, M. J., Busch, O. R. C., Besselink, M. G. H. (2016). Recent Advances in Pancreatic Cancer Surgery of Relevance to the Practicing Pathologist. Surgical Pathology Clinics, 9(4), 539-545. https://doi.org/10.1016/j.path.2016.05.002

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title = "Recent Advances in Pancreatic Cancer Surgery of Relevance to the Practicing Pathologist",

abstract = "Recent advances in pancreatic surgery have the potential to improve outcomes for patients with pancreatic cancer. We address 3 new, trending topics in pancreatic surgery that are of relevance to the pathologist. First, increasing awareness of the prognostic impact of intraoperatively detected extraregional and regional lymph node metastases and the international consensus definition on lymph node sampling and reporting. Second, neoadjuvant chemotherapy, which is capable of changing 10\% to 20\% of initially unresectable, to resectable disease. Third, in patients who remain unresectable following neoadjuvant chemotherapy, local ablative therapies may change indications for treatment and improve outcomes.",

keywords = "Whipple, Pancreatoduodenectomy, Pancreas, Surgery, Pathology, Lymph node, Neoadjuvant, Radiofrequency ablation",

author = "\{van Rijssen\}, \{Lennart B\} and Rombouts, \{Steffi J E\} and Walma, \{Marieke S\} and Vogel, \{Jantien A\} and Tol, \{Johanna A\} and IQ Molenaar and \{van Eijck\}, \{Casper H J\} and Joanne Verheij and \{van de Vijver\}, \{Marc J\} and Busch, \{Olivier R C\} and Besselink, \{Marc G H\}",

year = "2016",

month = dec,

doi = "10.1016/j.path.2016.05.002",

language = "English",

volume = "9",

pages = "539--545",

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AU - van Rijssen, Lennart B

AU - Rombouts, Steffi J E

AU - Walma, Marieke S

AU - Vogel, Jantien A

AU - Tol, Johanna A

AU - Molenaar, IQ

AU - van Eijck, Casper H J

AU - Verheij, Joanne

AU - van de Vijver, Marc J

AU - Busch, Olivier R C

AU - Besselink, Marc G H

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AB - Recent advances in pancreatic surgery have the potential to improve outcomes for patients with pancreatic cancer. We address 3 new, trending topics in pancreatic surgery that are of relevance to the pathologist. First, increasing awareness of the prognostic impact of intraoperatively detected extraregional and regional lymph node metastases and the international consensus definition on lymph node sampling and reporting. Second, neoadjuvant chemotherapy, which is capable of changing 10% to 20% of initially unresectable, to resectable disease. Third, in patients who remain unresectable following neoadjuvant chemotherapy, local ablative therapies may change indications for treatment and improve outcomes.

KW - Whipple

KW - Pancreatoduodenectomy

KW - Pancreas

KW - Surgery

KW - Pathology

KW - Lymph node

KW - Neoadjuvant

KW - Radiofrequency ablation

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DO - 10.1016/j.path.2016.05.002

M3 - Article

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EP - 545

JO - Surgical Pathology Clinics

JF - Surgical Pathology Clinics

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ER -

Recent Advances in Pancreatic Cancer Surgery of Relevance to the Practicing Pathologist

Abstract

Keywords

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