Raman spectroscopy-based identification of nosocomial outbreaks of the clonal bacterium Escherichia coli

J. G. Kusters; W. B. van Leeuwen; K. Maquelin; H. E M Blok; H. F M Willemse; L. A M de Graaf-Miltenburg; A. C. Fluit; A. Troelstra

doi:10.1007/s10096-015-2511-x

Raman spectroscopy-based identification of nosocomial outbreaks of the clonal bacterium Escherichia coli

J. G. Kusters^*, W. B. van Leeuwen, K. Maquelin, H. E M Blok, H. F M Willemse, L. A M de Graaf-Miltenburg, A. C. Fluit, A. Troelstra

^*Corresponding author for this work

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Abstract

DNA-based techniques are frequently used to confirm the relatedness of putative outbreak isolates. These techniques often lack the discriminatory power when analyzing closely related microbes such as E. coli. Here the value of Raman spectroscopy as a typing tool for E. coli in a clinical setting was retrospectively evaluated.

Original language	English
Pages (from-to)	83-87
Number of pages	5
Journal	European Journal of Clinical Microbiology & Infectious Diseases
Volume	35
Issue number	1
DOIs	https://doi.org/10.1007/s10096-015-2511-x
Publication status	Published - 1 Jan 2016

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Kusters, J. G., van Leeuwen, W. B., Maquelin, K., Blok, H. E. M., Willemse, H. F. M., de Graaf-Miltenburg, L. A. M., Fluit, A. C., & Troelstra, A. (2016). Raman spectroscopy-based identification of nosocomial outbreaks of the clonal bacterium Escherichia coli. European Journal of Clinical Microbiology & Infectious Diseases, 35(1), 83-87. https://doi.org/10.1007/s10096-015-2511-x

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AU - Willemse, H. F M

AU - de Graaf-Miltenburg, L. A M

AU - Fluit, A. C.

AU - Troelstra, A.

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Raman spectroscopy-based identification of nosocomial outbreaks of the clonal bacterium Escherichia coli

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