TY - JOUR
T1 - Radiation-Induced Giant Cell Granuloma Mimicking Relapsed Hodgkin Lymphoma at FDG-PET/CT
AU - Adams, Hugo J.A.
AU - de Klerk, John M. H.
AU - Regelink, Josien C.
AU - Heggelman, Ben G. F.
AU - Dubois, Stefan V.
AU - Kwee, Thomas C.
N1 - Funding Information:
We thank the Netherlands Committee on Bone Tumors for assistance in interpreting the histopathological slides. This manuscript has not been published before or is not under consideration for publication anywhere else and has been approved by all co-authors. Hugo J.A. Adams: no conflict of interest. John M.H. de Klerk: no conflict of interest. Josien C. Regelink: no conflict of interest. Ben. G.F. Heggelman: no conflict of interest. Stefan V. Dubois: no conflict of interest. Thomas C. Kwee; no conflict of interest. This work was financially supported by an Alpe d’HuZes/Dutch Cancer Society Bas Mulder Award for T.C.K. (grant number 5409). Data collection, data analysis, and interpretation of data, writing of the paper, and decision to submit were left to the authors’ discretion and were not influenced by Alpe d’HuZes/Dutch Cancer Society.
Funding Information:
Funding This work was financially supported by an Alpe d’HuZes/Dutch Cancer Society Bas Mulder Award for T.C.K. (grant number 5409). Data collection, data analysis, and interpretation of data, writing of the paper, and decision to submit were left to the authors’ discretion and were not influenced by Alpe d’HuZes/Dutch Cancer Society.
Publisher Copyright:
© 2016, Korean Society of Nuclear Medicine.
PY - 2017/12/1
Y1 - 2017/12/1
N2 - A 22-year-old woman was diagnosed with intermediate risk stage II Hodgkin lymphoma and treated with three cycles of adriamycin, bleomycin, vinblastine, and dacarbazine (ABVD) followed by involved-field radiation therapy. A complete metabolic remission was achieved after two cycles of ABVD, which was maintained until three years after completion of treatment. Follow-up FDG-PET/CT four years after completion of treatment, however, showed a new FDG-avid (Deauville score of 4) lesion in the right scapula, suggesting relapsed disease. Computer tomography (CT)-guided biopsy of this lesion was performed and subsequent histological examination revealed a radiation-induced giant cell granuloma.
AB - A 22-year-old woman was diagnosed with intermediate risk stage II Hodgkin lymphoma and treated with three cycles of adriamycin, bleomycin, vinblastine, and dacarbazine (ABVD) followed by involved-field radiation therapy. A complete metabolic remission was achieved after two cycles of ABVD, which was maintained until three years after completion of treatment. Follow-up FDG-PET/CT four years after completion of treatment, however, showed a new FDG-avid (Deauville score of 4) lesion in the right scapula, suggesting relapsed disease. Computer tomography (CT)-guided biopsy of this lesion was performed and subsequent histological examination revealed a radiation-induced giant cell granuloma.
KW - Biopsy
KW - FDG-PET/CT
KW - Giant cell granuloma
KW - Hodgkin lymphoma
UR - http://www.scopus.com/inward/record.url?scp=85037659778&partnerID=8YFLogxK
U2 - 10.1007/s13139-016-0426-9
DO - 10.1007/s13139-016-0426-9
M3 - Article
C2 - 29242737
AN - SCOPUS:85037659778
SN - 1869-3474
VL - 51
SP - 371
EP - 373
JO - Nuclear Medicine and Molecular Imaging
JF - Nuclear Medicine and Molecular Imaging
IS - 4
ER -