Radiation dose reduction in pediatric great vessel stent computed tomography using iterative reconstruction: A phantom study

Annemarie M den Harder; Dominika Suchá; Pieter J van Doormaal; Ricardo P J Budde; Pim A de Jong; Arnold M R Schilham; JMPJ Breur; Tim Leiner

doi:10.1371/journal.pone.0175714

Radiation dose reduction in pediatric great vessel stent computed tomography using iterative reconstruction: A phantom study

Annemarie M den Harder, Dominika Suchá, Pieter J van Doormaal, Ricardo P J Budde, Pim A de Jong, Arnold M R Schilham, JMPJ Breur, Tim Leiner

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

BACKGROUND: To study dose reduction using iterative reconstruction (IR) for pediatric great vessel stent computed tomography (CT).

METHODS: Five different great vessel stents were separately placed in a gel-containing plastic holder within an anthropomorphic chest phantom. The stent lumen was filled with diluted contrast gel. CT acquisitions were performed at routine dose, 52% and 81% reduced dose and reconstructed with filtered back projection (FBP) and IR. Objective image quality in terms of noise, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) as well as subjective image quality were evaluated.

RESULTS: Noise, SNR and CNR were improved with IR at routine and 52% reduced dose, compared to FBP at routine dose. The lowest dose level resulted in decreased objective image quality with both FBP and IR. Subjective image quality was excellent at all dose levels.

CONCLUSION: IR resulted in improved objective image quality at routine dose and 52% reduced dose, while objective image quality deteriorated at 81% reduced dose. Subjective image quality was not affected by dose reduction.

Original language	English
Article number	e0175714
Journal	PLoS ONE [E]
Volume	12
Issue number	4
DOIs	https://doi.org/10.1371/journal.pone.0175714
Publication status	Published - 2017

Keywords

Computed axial tomography
Coronary stenting
Infrared radiation
Pedriatrics
angiography
noise reduction
signal to noise ratio
stent implantation

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@article{ec3c86e317384c4a90eb783a9026332d,

title = "Radiation dose reduction in pediatric great vessel stent computed tomography using iterative reconstruction: A phantom study",

abstract = "BACKGROUND: To study dose reduction using iterative reconstruction (IR) for pediatric great vessel stent computed tomography (CT).METHODS: Five different great vessel stents were separately placed in a gel-containing plastic holder within an anthropomorphic chest phantom. The stent lumen was filled with diluted contrast gel. CT acquisitions were performed at routine dose, 52% and 81% reduced dose and reconstructed with filtered back projection (FBP) and IR. Objective image quality in terms of noise, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) as well as subjective image quality were evaluated.RESULTS: Noise, SNR and CNR were improved with IR at routine and 52% reduced dose, compared to FBP at routine dose. The lowest dose level resulted in decreased objective image quality with both FBP and IR. Subjective image quality was excellent at all dose levels.CONCLUSION: IR resulted in improved objective image quality at routine dose and 52% reduced dose, while objective image quality deteriorated at 81% reduced dose. Subjective image quality was not affected by dose reduction.",

keywords = "Computed axial tomography, Coronary stenting , Infrared radiation , Pedriatrics, angiography, noise reduction, signal to noise ratio, stent implantation",

author = "{den Harder}, {Annemarie M} and Dominika Such{\'a} and {van Doormaal}, {Pieter J} and Budde, {Ricardo P J} and {de Jong}, {Pim A} and Schilham, {Arnold M R} and JMPJ Breur and Tim Leiner",

note = "Publisher Copyright: {\textcopyright} 2017 den Harder et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.",

year = "2017",

doi = "10.1371/journal.pone.0175714",

language = "English",

volume = "12",

journal = "PLoS ONE [E]",

issn = "1932-6203",

publisher = "Public Library of Science",

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TY - JOUR

T1 - Radiation dose reduction in pediatric great vessel stent computed tomography using iterative reconstruction

T2 - A phantom study

AU - den Harder, Annemarie M

AU - Suchá, Dominika

AU - van Doormaal, Pieter J

AU - Budde, Ricardo P J

AU - de Jong, Pim A

AU - Schilham, Arnold M R

AU - Breur, JMPJ

AU - Leiner, Tim

N1 - Publisher Copyright: © 2017 den Harder et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PY - 2017

Y1 - 2017

N2 - BACKGROUND: To study dose reduction using iterative reconstruction (IR) for pediatric great vessel stent computed tomography (CT).METHODS: Five different great vessel stents were separately placed in a gel-containing plastic holder within an anthropomorphic chest phantom. The stent lumen was filled with diluted contrast gel. CT acquisitions were performed at routine dose, 52% and 81% reduced dose and reconstructed with filtered back projection (FBP) and IR. Objective image quality in terms of noise, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) as well as subjective image quality were evaluated.RESULTS: Noise, SNR and CNR were improved with IR at routine and 52% reduced dose, compared to FBP at routine dose. The lowest dose level resulted in decreased objective image quality with both FBP and IR. Subjective image quality was excellent at all dose levels.CONCLUSION: IR resulted in improved objective image quality at routine dose and 52% reduced dose, while objective image quality deteriorated at 81% reduced dose. Subjective image quality was not affected by dose reduction.

AB - BACKGROUND: To study dose reduction using iterative reconstruction (IR) for pediatric great vessel stent computed tomography (CT).METHODS: Five different great vessel stents were separately placed in a gel-containing plastic holder within an anthropomorphic chest phantom. The stent lumen was filled with diluted contrast gel. CT acquisitions were performed at routine dose, 52% and 81% reduced dose and reconstructed with filtered back projection (FBP) and IR. Objective image quality in terms of noise, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) as well as subjective image quality were evaluated.RESULTS: Noise, SNR and CNR were improved with IR at routine and 52% reduced dose, compared to FBP at routine dose. The lowest dose level resulted in decreased objective image quality with both FBP and IR. Subjective image quality was excellent at all dose levels.CONCLUSION: IR resulted in improved objective image quality at routine dose and 52% reduced dose, while objective image quality deteriorated at 81% reduced dose. Subjective image quality was not affected by dose reduction.

KW - Computed axial tomography

KW - Coronary stenting

KW - Infrared radiation

KW - Pedriatrics

KW - angiography

KW - noise reduction

KW - signal to noise ratio

KW - stent implantation

U2 - 10.1371/journal.pone.0175714

DO - 10.1371/journal.pone.0175714

M3 - Article

C2 - 28410386

SN - 1932-6203

VL - 12

JO - PLoS ONE [E]

JF - PLoS ONE [E]

IS - 4

M1 - e0175714

ER -

Radiation dose reduction in pediatric great vessel stent computed tomography using iterative reconstruction: A phantom study

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