Quantitative MRI of the human brain at 7 tesla

D.L. Polders

Research output: ThesisDoctoral thesis 1 (Research UU / Graduation UU)


This thesis describes the implementation of quantitative MR methods in the human brain at 7 T. By highlighting the drawbacks and advantages of the increased field strength, the use of 7 T MRI for quantitative measurements in clinical research was demonstrated. Inhomogeneities in the transmitted RF field limit the feasibility of methods that rely on the application of homogeneous RF pulses. The increased SNR at this high field strength enables rapid acquisition of high quality imaging volumes suitable for quantitative modeling while at the same time decreasing the uncertainty in fitted parameters.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Utrecht University
  • Luijten, Peter, Primary supervisor
  • Hoogduin, JM, Co-supervisor
Award date11 Dec 2012
Print ISBNs978-908-8915-18-5
Publication statusPublished - 11 Dec 2012


  • Econometric and Statistical Methods: General
  • Geneeskunde(GENK)
  • Medical sciences
  • Bescherming en bevordering van de menselijke gezondheid


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