Quantitative MRI of the human brain at 7 tesla

D.L. Polders

Quantitative MRI of the human brain at 7 tesla

D.L. Polders

Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

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Abstract

This thesis describes the implementation of quantitative MR methods in the human brain at 7 T. By highlighting the drawbacks and advantages of the increased field strength, the use of 7 T MRI for quantitative measurements in clinical research was demonstrated. Inhomogeneities in the transmitted RF field limit the feasibility of methods that rely on the application of homogeneous RF pulses. The increased SNR at this high field strength enables rapid acquisition of high quality imaging volumes suitable for quantitative modeling while at the same time decreasing the uncertainty in fitted parameters.

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	Utrecht University
Supervisors/Advisors	Luijten, Peter, Primary supervisor Hoogduin, Hans, Co-supervisor
Award date	11 Dec 2012
Print ISBNs	978-908-8915-18-5
Publication status	Published - 11 Dec 2012

Keywords

Econometric and Statistical Methods: General
Geneeskunde(GENK)
Medical sciences
Bescherming en bevordering van de menselijke gezondheid

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abstract = "This thesis describes the implementation of quantitative MR methods in the human brain at 7 T. By highlighting the drawbacks and advantages of the increased field strength, the use of 7 T MRI for quantitative measurements in clinical research was demonstrated. Inhomogeneities in the transmitted RF field limit the feasibility of methods that rely on the application of homogeneous RF pulses. The increased SNR at this high field strength enables rapid acquisition of high quality imaging volumes suitable for quantitative modeling while at the same time decreasing the uncertainty in fitted parameters.",

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AB - This thesis describes the implementation of quantitative MR methods in the human brain at 7 T. By highlighting the drawbacks and advantages of the increased field strength, the use of 7 T MRI for quantitative measurements in clinical research was demonstrated. Inhomogeneities in the transmitted RF field limit the feasibility of methods that rely on the application of homogeneous RF pulses. The increased SNR at this high field strength enables rapid acquisition of high quality imaging volumes suitable for quantitative modeling while at the same time decreasing the uncertainty in fitted parameters.

KW - Econometric and Statistical Methods: General

KW - Geneeskunde(GENK)

KW - Medical sciences

KW - Bescherming en bevordering van de menselijke gezondheid

M3 - Doctoral thesis 1 (Research UU / Graduation UU)

SN - 978-908-8915-18-5

ER -

Quantitative MRI of the human brain at 7 tesla

Abstract

Keywords

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