TY - JOUR
T1 - Qualitative grading of aortic regurgitation
T2 - a pilot study comparing CMR 4D flow and echocardiography
AU - Chelu, Raluca G.
AU - van den Bosch, Annemien E.
AU - van Kranenburg, Matthijs
AU - Hsiao, Albert
AU - van den Hoven, Allard T.
AU - Ouhlous, Mohamed
AU - Budde, Ricardo P J
AU - Beniest, Kirsten M.
AU - Swart, Laurens E.
AU - Coenen, Adriaan
AU - Lubbers, Marisa M.
AU - Wielopolski, Piotr A.
AU - Vasanawala, Shreyas S.
AU - Roos-Hesselink, Jolien W.
AU - Nieman, Koen
PY - 2016/2/1
Y1 - 2016/2/1
N2 - Over the past 10 years there has been intense research in the development of volumetric visualization of intracardiac flow by cardiac magnetic resonance (CMR). This volumetric time resolved technique called CMR 4D flow imaging has several advantages over standard CMR. It offers anatomical, functional and flow information in a single free-breathing, ten-minute acquisition. However, the data obtained is large and its processing requires dedicated software. We evaluated a cloud-based application package that combines volumetric data correction and visualization of CMR 4D flow data, and assessed its accuracy for the detection and grading of aortic valve regurgitation using transthoracic echocardiography as reference. Between June 2014 and January 2015, patients planned for clinical CMR were consecutively approached to undergo the supplementary CMR 4D flow acquisition. Fifty four patients (median age 39 years, 32 males) were included. Detection and grading of the aortic valve regurgitation using CMR 4D flow imaging were evaluated against transthoracic echocardiography. The agreement between 4D flow CMR and transthoracic echocardiography for grading of aortic valve regurgitation was good (κ = 0.73). To identify relevant, more than mild aortic valve regurgitation, CMR 4D flow imaging had a sensitivity of 100 % and specificity of 98 %. Aortic regurgitation can be well visualized, in a similar manner as transthoracic echocardiography, when using CMR 4D flow imaging.
AB - Over the past 10 years there has been intense research in the development of volumetric visualization of intracardiac flow by cardiac magnetic resonance (CMR). This volumetric time resolved technique called CMR 4D flow imaging has several advantages over standard CMR. It offers anatomical, functional and flow information in a single free-breathing, ten-minute acquisition. However, the data obtained is large and its processing requires dedicated software. We evaluated a cloud-based application package that combines volumetric data correction and visualization of CMR 4D flow data, and assessed its accuracy for the detection and grading of aortic valve regurgitation using transthoracic echocardiography as reference. Between June 2014 and January 2015, patients planned for clinical CMR were consecutively approached to undergo the supplementary CMR 4D flow acquisition. Fifty four patients (median age 39 years, 32 males) were included. Detection and grading of the aortic valve regurgitation using CMR 4D flow imaging were evaluated against transthoracic echocardiography. The agreement between 4D flow CMR and transthoracic echocardiography for grading of aortic valve regurgitation was good (κ = 0.73). To identify relevant, more than mild aortic valve regurgitation, CMR 4D flow imaging had a sensitivity of 100 % and specificity of 98 %. Aortic regurgitation can be well visualized, in a similar manner as transthoracic echocardiography, when using CMR 4D flow imaging.
KW - Aortic regurgitation
KW - Cardiac
KW - CMR 4D flow imaging
KW - Eddy currents correction
KW - Flow visualization
KW - Phase contrast
UR - http://www.scopus.com/inward/record.url?scp=84957435392&partnerID=8YFLogxK
U2 - 10.1007/s10554-015-0779-7
DO - 10.1007/s10554-015-0779-7
M3 - Article
C2 - 26498478
AN - SCOPUS:84957435392
SN - 1569-5794
VL - 32
SP - 301
EP - 307
JO - The International Journal of Cardiovascular Imaging
JF - The International Journal of Cardiovascular Imaging
IS - 2
ER -