Pulmonary Complications of Childhood Cancer Treatment

AB Versluijs, Dorine Bresters

Research output: Contribution to journalArticleAcademicpeer-review


Pulmonary complications of childhood cancer treatment are frequently seen. These can lead to adverse sequelae many years after treatment, with important impact on morbidity, quality of life and mortality in childhood cancer survivors. This review addresses the effects of chemotherapy, radiotherapy, surgery and alloimmunity (in haematopoietic cell transplantation) on the lung in children. It highlights the complexity of lung damage and lung disease in relation to growth and development, infections and other external factors. Screening high risk childhood cancer survivors for treatment related late effects, with therapy based screening protocols, using full medical assessment and pulmonary function tests is important. This will lead to recognition of pulmonary sequelae of cancer treatment, early detection of lung damage in survivors and better treatment and prevention.

Original languageEnglish
Pages (from-to)63–70
JournalPaediatric Respiratory Reviews [E]
Publication statusPublished - 2016


  • Pulmonary complications
  • Lung injury
  • Childhood cancer survivors
  • Chemotherapy late effects
  • Irradiation late effects


Dive into the research topics of 'Pulmonary Complications of Childhood Cancer Treatment'. Together they form a unique fingerprint.

Cite this