Psychiatrische symptomen en COVID-19: resultaten uit een landelijk register

Translated title of the contribution: Psychiatric symptoms and COVID-19: results of a national case register

V. van Dee, E. A.M. Janssen, R. M. Blom, W. Cahn, H. C. van Mierlo, R. Mihaescu, J. van Wullften Palthe, R. Zijlstra, R. M. Kok, D. S. Everaerd, A. Schellekens, C. oviP-Consortium

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

BACKGROUND: Psychiatric disorders are associated with a more severe course of COVID-19. COVID-19 can also lead to psychiatric symptoms. AIM: To gain insight into vulnerabilities and protective factors for the course of COVID-19 in a Dutch (neuro)psychiatric population. METHOD: Patients were divided into three groups: patients with pre-existent mental disorders without and with new (neuro)psychiatric symptoms (NPS) during COVID-19 and patients without pre-existent mental disorders who developed de novo NPS during COVID-19. We summarize the characteristics of each group and compare the subgroups with inferential statistics. RESULTS: 186 patients were included in the case register. Patients with NPS showed a more severe course of COVID-19. Mortality in patients with NPS was higher in patients with pre-existent mental disorders compared to patients without pre-existent mental disorders. The most frequently reported de novo psychiatric symptoms during COVID-19 were delirium (46-70%), anxiety (53-54%) and insomnia (18-42%). CONCLUSION: NPS might be an expression of a more severe COVID-19 episode. In patients who developed NPS during COVID-19 we found evidence for a higher mortality risk in patients with pre-existent mental disorders. Extra vigilance for neuropsychiatric symptoms during COVID-19 is warranted.

Translated title of the contributionPsychiatric symptoms and COVID-19: results of a national case register
Original languageDutch
Pages (from-to)558-565
Number of pages8
JournalTijdschrift voor Psychiatrie
Volume64
Issue number9
Publication statusPublished - 2022

Keywords

  • Humans
  • COVID-19
  • Mental Disorders/epidemiology
  • Anxiety/epidemiology
  • Sleep Initiation and Maintenance Disorders
  • Anxiety Disorders

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