PSMA-PET: aanwinst voor de prostaatkankerdiagnostiek

Esmée C.A. van der Sar; Jules Lavalaye; Arthur J.A.T. Braat; John M.H. de Klerk; Marnix G.E.H. Lam; Bart de Keizer

PSMA-PET: aanwinst voor de prostaatkankerdiagnostiek

Translated title of the contribution: PSMA PET, an important addition in prostate cancer diagnostics

Esmée C.A. van der Sar^*, Jules Lavalaye, Arthur J.A.T. Braat, John M.H. de Klerk, Marnix G.E.H. Lam, Bart de Keizer

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

SMA PET/CT is a diagnostic technique for patients with prostate cancer. It makes use of a radioligand that specifically binds to 'prostate specific membrane antigen' (PSMA), expressed by the prostate cancer cells. PSMA PET has proven to be highly effective in prostate cancer diagnostics in both primary staging and re-staging. PSMA PET/CT has a much higher accuracy than traditional CT and skeletal scintigraphy for the detection of metastases, allowing metastases to be detected in an earlier stage. The clinical relevance of the improved detection is now under investigation. Staging with PSMA PET/CT sometimes leads to avoiding surgery because distant metastases are found that were not detected with conventional imaging. In the Netherlands, PSMA PET/CT is now indicated both in primary prostate cancer diagnostics for the detection of metastases and for the detection of biochemical recurrence after prostatectomy or after radiotherapy.

Translated title of the contribution	PSMA PET, an important addition in prostate cancer diagnostics
Original language	Dutch
Article number	D6950
Number of pages	4
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	167
Issue number	2
Publication status	Published - 4 Jan 2023

Access to Document

https://www.ntvg.nl/artikelen/psma-pet-aanwinst-voor-de-prostaatkankerdiagnostiek

Cite this

@article{82550e76ea484318b1842ee352e0b065,

title = "PSMA-PET: aanwinst voor de prostaatkankerdiagnostiek",

abstract = "SMA PET/CT is a diagnostic technique for patients with prostate cancer. It makes use of a radioligand that specifically binds to 'prostate specific membrane antigen' (PSMA), expressed by the prostate cancer cells. PSMA PET has proven to be highly effective in prostate cancer diagnostics in both primary staging and re-staging. PSMA PET/CT has a much higher accuracy than traditional CT and skeletal scintigraphy for the detection of metastases, allowing metastases to be detected in an earlier stage. The clinical relevance of the improved detection is now under investigation. Staging with PSMA PET/CT sometimes leads to avoiding surgery because distant metastases are found that were not detected with conventional imaging. In the Netherlands, PSMA PET/CT is now indicated both in primary prostate cancer diagnostics for the detection of metastases and for the detection of biochemical recurrence after prostatectomy or after radiotherapy.",

author = "{van der Sar}, {Esm{\'e}e C.A.} and Jules Lavalaye and Braat, {Arthur J.A.T.} and {de Klerk}, {John M.H.} and Lam, {Marnix G.E.H.} and {de Keizer}, Bart",

year = "2023",

month = jan,

day = "4",

language = "Dutch",

volume = "167",

journal = "Nederlands Tijdschrift voor Geneeskunde",

issn = "0028-2162",

publisher = "Bohn Stafleu van Loghum",

number = "2",

}

TY - JOUR

T1 - PSMA-PET

T2 - aanwinst voor de prostaatkankerdiagnostiek

AU - van der Sar, Esmée C.A.

AU - Lavalaye, Jules

AU - Braat, Arthur J.A.T.

AU - de Klerk, John M.H.

AU - Lam, Marnix G.E.H.

AU - de Keizer, Bart

PY - 2023/1/4

Y1 - 2023/1/4

N2 - SMA PET/CT is a diagnostic technique for patients with prostate cancer. It makes use of a radioligand that specifically binds to 'prostate specific membrane antigen' (PSMA), expressed by the prostate cancer cells. PSMA PET has proven to be highly effective in prostate cancer diagnostics in both primary staging and re-staging. PSMA PET/CT has a much higher accuracy than traditional CT and skeletal scintigraphy for the detection of metastases, allowing metastases to be detected in an earlier stage. The clinical relevance of the improved detection is now under investigation. Staging with PSMA PET/CT sometimes leads to avoiding surgery because distant metastases are found that were not detected with conventional imaging. In the Netherlands, PSMA PET/CT is now indicated both in primary prostate cancer diagnostics for the detection of metastases and for the detection of biochemical recurrence after prostatectomy or after radiotherapy.

AB - SMA PET/CT is a diagnostic technique for patients with prostate cancer. It makes use of a radioligand that specifically binds to 'prostate specific membrane antigen' (PSMA), expressed by the prostate cancer cells. PSMA PET has proven to be highly effective in prostate cancer diagnostics in both primary staging and re-staging. PSMA PET/CT has a much higher accuracy than traditional CT and skeletal scintigraphy for the detection of metastases, allowing metastases to be detected in an earlier stage. The clinical relevance of the improved detection is now under investigation. Staging with PSMA PET/CT sometimes leads to avoiding surgery because distant metastases are found that were not detected with conventional imaging. In the Netherlands, PSMA PET/CT is now indicated both in primary prostate cancer diagnostics for the detection of metastases and for the detection of biochemical recurrence after prostatectomy or after radiotherapy.

UR - http://www.scopus.com/inward/record.url?scp=85146141138&partnerID=8YFLogxK

M3 - Article

C2 - 36633055

AN - SCOPUS:85146141138

SN - 0028-2162

VL - 167

JO - Nederlands Tijdschrift voor Geneeskunde

JF - Nederlands Tijdschrift voor Geneeskunde

IS - 2

M1 - D6950

ER -

PSMA-PET: aanwinst voor de prostaatkankerdiagnostiek

Abstract

Access to Document

Other files and links

Fingerprint

Cite this