Proton Pump Inhibitor Use Is Associated With Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Rectal Carriage at Hospital Admission: A Cross-Sectional Study

Pepijn Huizinga; Marjolein Kluytmans- van den Bergh; Miranda van Rijen; Ina Willemsen; Nils van 't Veer; Jan Kluytmans

doi:10.1093/cid/ciw743

Proton Pump Inhibitor Use Is Associated With Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Rectal Carriage at Hospital Admission: A Cross-Sectional Study

Pepijn Huizinga^*
, Marjolein Kluytmans- van den Bergh
, Miranda van Rijen
, Ina Willemsen
, Nils van 't Veer
, Jan Kluytmans

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

In this cross-sectional study, 8.5% of patients using proton pump inhibitors (PPIs) were rectal carriers of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E), compared with 2.9% of non-PPI users. In multivariable analysis, PPI use was independently associated with ESBL-E rectal carriage at hospital admission (adjusted odds ratio, 3.89; 95% confidence interval, 1.65 - 9.19).

Original language	English
Pages (from-to)	361-363
Number of pages	3
Journal	Clinical Infectious Diseases
Volume	64
Issue number	3
DOIs	https://doi.org/10.1093/cid/ciw743
Publication status	Published - 1 Feb 2017

Keywords

Carriage
ESBL
Proton pump inhibitor
Risk factor

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10.1093/cid/ciw743

ProtonFinal published version, 99 KBLicence: Taverne

Cite this

@article{4fa3ee679e434e74ab38854b84c9123e,

title = "Proton Pump Inhibitor Use Is Associated With Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Rectal Carriage at Hospital Admission: A Cross-Sectional Study",

abstract = "In this cross-sectional study, 8.5\% of patients using proton pump inhibitors (PPIs) were rectal carriers of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E), compared with 2.9\% of non-PPI users. In multivariable analysis, PPI use was independently associated with ESBL-E rectal carriage at hospital admission (adjusted odds ratio, 3.89; 95\% confidence interval, 1.65 - 9.19).",

keywords = "Carriage, ESBL, Proton pump inhibitor, Risk factor",

author = "Pepijn Huizinga and \{van den Bergh\}, \{Marjolein Kluytmans-\} and \{van Rijen\}, Miranda and Ina Willemsen and \{van 't Veer\}, Nils and Jan Kluytmans",

year = "2017",

month = feb,

day = "1",

doi = "10.1093/cid/ciw743",

language = "English",

volume = "64",

pages = "361--363",

journal = "Clinical Infectious Diseases",

issn = "1058-4838",

publisher = "Oxford University Press",

number = "3",

}

Proton Pump Inhibitor Use Is Associated With Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Rectal Carriage at Hospital Admission: A Cross-Sectional Study. / Huizinga, Pepijn; van den Bergh, Marjolein Kluytmans-; van Rijen, Miranda et al.
In: Clinical Infectious Diseases, Vol. 64, No. 3, 01.02.2017, p. 361-363.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Proton Pump Inhibitor Use Is Associated With Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Rectal Carriage at Hospital Admission

T2 - A Cross-Sectional Study

AU - Huizinga, Pepijn

AU - van den Bergh, Marjolein Kluytmans-

AU - van Rijen, Miranda

AU - Willemsen, Ina

AU - van 't Veer, Nils

AU - Kluytmans, Jan

PY - 2017/2/1

Y1 - 2017/2/1

N2 - In this cross-sectional study, 8.5% of patients using proton pump inhibitors (PPIs) were rectal carriers of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E), compared with 2.9% of non-PPI users. In multivariable analysis, PPI use was independently associated with ESBL-E rectal carriage at hospital admission (adjusted odds ratio, 3.89; 95% confidence interval, 1.65 - 9.19).

AB - In this cross-sectional study, 8.5% of patients using proton pump inhibitors (PPIs) were rectal carriers of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E), compared with 2.9% of non-PPI users. In multivariable analysis, PPI use was independently associated with ESBL-E rectal carriage at hospital admission (adjusted odds ratio, 3.89; 95% confidence interval, 1.65 - 9.19).

KW - Carriage

KW - ESBL

KW - Proton pump inhibitor

KW - Risk factor

UR - https://www.scopus.com/pages/publications/85019105109

U2 - 10.1093/cid/ciw743

DO - 10.1093/cid/ciw743

M3 - Article

C2 - 27965302

SN - 1058-4838

VL - 64

SP - 361

EP - 363

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

IS - 3

ER -

Proton Pump Inhibitor Use Is Associated With Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Rectal Carriage at Hospital Admission: A Cross-Sectional Study

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Keywords

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