Protocolized versus non-protocolized weaning for reducing the duration of invasive mechanical ventilation in newborn infants

This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the efficacy of protocolized versus non-protocolized ventilator weaning for newborn infants in reducing the duration of invasive mechanical ventilation and the duration of weaning, and shortening the NICU and hospital length of stay. To determine efficacy in predefined subgroups including: (1) gestational age and weight, (2) type of protocol, (3) type of protocol delivery. To establish whether protocolized weaning is safe and clinically effective in reducing the duration of mechanical ventilation without increasing the risk of adverse events.