Abstract
Protein-tyrosine phosphatases are tightly controlled by various mechanisms, ranging from differential expression in specific cell types to restricted subcellular localization, limited proteolysis, post-translational modifications affecting intrinsic catalytic activity, ligand binding and dimerization. Here, we review the regulatory mechanisms found to control the classical protein-tyrosine phosphatases
| Translated title of the contribution | Protein tyrosine phosphatases: regulatory mechanisms |
|---|---|
| Original language | Undefined/Unknown |
| Pages (from-to) | 831-847 |
| Number of pages | 17 |
| Journal | The FEBS journal |
| Volume | 275 |
| Issue number | 5 |
| Publication status | Published - 2008 |