Prolonged Shedding of Human Parechovirus in Feces of Young Children after Symptomatic Infection

Joanne G Wildenbeest; Kimberley S M Benschop; Saskia Bouma-de Jongh; Katja C Wolthers; Dasja Pajkrt

doi:10.1097/INF.0000000000001082

Prolonged Shedding of Human Parechovirus in Feces of Young Children after Symptomatic Infection

Joanne G Wildenbeest, Kimberley S M Benschop, Saskia Bouma-de Jongh, Katja C Wolthers, Dasja Pajkrt

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

After symptomatic human parechovirus (HPeV) infection in infants, the duration of (mostly asymptomatic) shedding in feces was 2-24 weeks (median 58 days). HPeV cycle threshold value could neither differentiate between symptomatic disease and asymptomatic shedding nor between severe and mild disease as high cycle threshold values (indicating low viral loads) were observed in HPeV3-infected children with severe disease.

Original language	English
Pages (from-to)	580-583
Number of pages	4
Journal	The Pediatric infectious disease journal
Volume	35
Issue number	5
DOIs	https://doi.org/10.1097/INF.0000000000001082
Publication status	Published - 2016

Keywords

Case-Control Studies
Feces
Female
Humans
Infant
Infant, Newborn
Ct-value
Parechovirus
Picornaviridae Infections
Prospective Studies
Time Factors
HPeV
Multicenter Study
shedding

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10.1097/INF.0000000000001082

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title = "Prolonged Shedding of Human Parechovirus in Feces of Young Children after Symptomatic Infection",

abstract = "After symptomatic human parechovirus (HPeV) infection in infants, the duration of (mostly asymptomatic) shedding in feces was 2-24 weeks (median 58 days). HPeV cycle threshold value could neither differentiate between symptomatic disease and asymptomatic shedding nor between severe and mild disease as high cycle threshold values (indicating low viral loads) were observed in HPeV3-infected children with severe disease.",

keywords = "Case-Control Studies, Feces, Female, Humans, Infant, Infant, Newborn, Ct-value, Parechovirus, Picornaviridae Infections, Prospective Studies, Time Factors, HPeV, Multicenter Study, shedding",

author = "Wildenbeest, {Joanne G} and Benschop, {Kimberley S M} and {Bouma-de Jongh}, Saskia and Wolthers, {Katja C} and Dasja Pajkrt",

year = "2016",

doi = "10.1097/INF.0000000000001082",

language = "English",

volume = "35",

pages = "580--583",

journal = "The Pediatric infectious disease journal",

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T1 - Prolonged Shedding of Human Parechovirus in Feces of Young Children after Symptomatic Infection

AU - Wildenbeest, Joanne G

AU - Benschop, Kimberley S M

AU - Bouma-de Jongh, Saskia

AU - Wolthers, Katja C

AU - Pajkrt, Dasja

PY - 2016

Y1 - 2016

N2 - After symptomatic human parechovirus (HPeV) infection in infants, the duration of (mostly asymptomatic) shedding in feces was 2-24 weeks (median 58 days). HPeV cycle threshold value could neither differentiate between symptomatic disease and asymptomatic shedding nor between severe and mild disease as high cycle threshold values (indicating low viral loads) were observed in HPeV3-infected children with severe disease.

AB - After symptomatic human parechovirus (HPeV) infection in infants, the duration of (mostly asymptomatic) shedding in feces was 2-24 weeks (median 58 days). HPeV cycle threshold value could neither differentiate between symptomatic disease and asymptomatic shedding nor between severe and mild disease as high cycle threshold values (indicating low viral loads) were observed in HPeV3-infected children with severe disease.

KW - Case-Control Studies

KW - Feces

KW - Female

KW - Humans

KW - Infant

KW - Infant, Newborn

KW - Ct-value

KW - Parechovirus

KW - Picornaviridae Infections

KW - Prospective Studies

KW - Time Factors

KW - HPeV

KW - Multicenter Study

KW - shedding

U2 - 10.1097/INF.0000000000001082

DO - 10.1097/INF.0000000000001082

M3 - Article

C2 - 26862672

SN - 0891-3668

VL - 35

SP - 580

EP - 583

JO - The Pediatric infectious disease journal

JF - The Pediatric infectious disease journal

IS - 5

ER -

Prolonged Shedding of Human Parechovirus in Feces of Young Children after Symptomatic Infection

Abstract

Keywords

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