Prolonged carriage and potential onward transmission of carbapenemase-producing Enterobacteriaceae in Dutch travelers

Jarne M. Van Hattem, Maris S. Arcilla, Martin C J Bootsma, Perry J. Van Genderen, Abraham Goorhuis, Martin P. Grobusch, Nicky Molhoek, Astrid M L Oude Lashof, Constance Schultsz, Ellen E. Stobberingh, Henri A. Verbrugh, Menno D. De Jong, Damian C. Melles, John Penders*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Abstract

Aim: The aim was to study acquisition and persistence of carbapenemase-producing Enterobacteriaceae (CPE) among travelers. Materials & methods: Stools from 2001 travelers and 215 nontraveling household members, collected before and immediately post-travel as well as 1, 3, 6 and 12 months upon return, were screened for CPE. Results: Five travelers, all visiting Asia outside the Indian subcontinent, acquired CPE. One traveler persistently carried the same OXA-244 CPE up to 6 months post-travel. Three months after travel, her co-traveling spouse also became positive for this OXA-244 CPE strain, suggesting clonal transmission within this household. Conclusion: Acquisition of CPE is not restricted to travelers to the Indian subcontinent and/or to travelers seeking healthcare during travel and can persist up to at least 6 months post-travel.

Original languageEnglish
Pages (from-to)857-864
Number of pages8
JournalFuture microbiology
Volume11
Issue number7
DOIs
Publication statusPublished - 1 Jul 2016

Keywords

  • carbapenemases
  • Enterobacteriaceae
  • transmission
  • travel

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