Prognostic testing for ovarian reserve

Simone L. Broer, Charlotte H.E. Weimar, Bart C.J.M. Fauser, Frank J. Broekmans

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Abstract

With the postponement of childbearing in Western societies, rates of sub-fertility related to advanced female age have increased considerably [1]. A higher proportion of couples therefore depends on assisted reproduction technology (ART) to achieve a pregnancy. The increase of sub-fertility with advanced female age is mainly based on changes in ovarian function referred to as decreased or diminished ovarian reserve. Ovarian reserve can be defined as the quantity and the quality of the remaining oocytes in both ovaries at a given age. Declines in follicle numbers dictate the occurrence of irregular cycles and ultimately the cessation of menstrual bleeding (i.e. menopause), whereas oocyte quality decay results in decreasing fertility, defined as the capacity to conceive and give birth to a child (Figure 38.1) [2].

Original languageEnglish
Title of host publicationTextbook of Assisted Reproductive Techniques
Subtitle of host publicationVolume 2: Clinical Perspectives, Sixth Edition
PublisherCRC Press
Pages409-418
Number of pages10
Volume2
ISBN (Electronic)9781000933505
ISBN (Print)9781032214801
DOIs
Publication statusPublished - 1 Jan 2023

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