Abstract
With the postponement of childbearing in Western societies, rates of sub-fertility related to advanced female age have increased considerably [1]. A higher proportion of couples therefore depends on assisted reproduction technology (ART) to achieve a pregnancy. The increase of sub-fertility with advanced female age is mainly based on changes in ovarian function referred to as decreased or diminished ovarian reserve. Ovarian reserve can be defined as the quantity and the quality of the remaining oocytes in both ovaries at a given age. Declines in follicle numbers dictate the occurrence of irregular cycles and ultimately the cessation of menstrual bleeding (i.e. menopause), whereas oocyte quality decay results in decreasing fertility, defined as the capacity to conceive and give birth to a child (Figure 38.1) [2].
Original language | English |
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Title of host publication | Textbook of Assisted Reproductive Techniques |
Subtitle of host publication | Volume 2: Clinical Perspectives, Sixth Edition |
Publisher | CRC Press |
Pages | 409-418 |
Number of pages | 10 |
Volume | 2 |
ISBN (Electronic) | 9781000933505 |
ISBN (Print) | 9781032214801 |
DOIs | |
Publication status | Published - 1 Jan 2023 |