Primed to perish: heightened mitochondrial priming explains hESC apoptosis sensitivity

N. Geijsen

Primed to perish: heightened mitochondrial priming explains hESC apoptosis sensitivity

N. Geijsen

Regenerative Medicine and Stem Cells

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Abstract Human embryonic stem cells (hESCs) are hypersensitive to apoptotic stimuli, though the underlying mechanisms are poorly characterized. In this issue of Cell Stem Cell, Liu et al. (2013) report that mitochondria of human ESCs exist in an apoptosis-prone state, ready to act as cellular executioners upon detecting DNA damage. Copyright © 2013 Elsevier Inc. All rights reserved.

Original language	English
Pages (from-to)	371-372
Number of pages	2
Journal	Cell Stem Cell
Volume	13
Publication status	Published - 2013

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title = "Primed to perish: heightened mitochondrial priming explains hESC apoptosis sensitivity",

abstract = "Abstract Human embryonic stem cells (hESCs) are hypersensitive to apoptotic stimuli, though the underlying mechanisms are poorly characterized. In this issue of Cell Stem Cell, Liu et al. (2013) report that mitochondria of human ESCs exist in an apoptosis-prone state, ready to act as cellular executioners upon detecting DNA damage. Copyright {\textcopyright} 2013 Elsevier Inc. All rights reserved.",

author = "N. Geijsen",

year = "2013",

language = "English",

volume = "13",

pages = "371--372",

journal = "Cell Stem Cell",

issn = "1934-5909",

publisher = "Cell Press",

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T1 - Primed to perish: heightened mitochondrial priming explains hESC apoptosis sensitivity

AU - Geijsen, N.

PY - 2013

Y1 - 2013

N2 - Abstract Human embryonic stem cells (hESCs) are hypersensitive to apoptotic stimuli, though the underlying mechanisms are poorly characterized. In this issue of Cell Stem Cell, Liu et al. (2013) report that mitochondria of human ESCs exist in an apoptosis-prone state, ready to act as cellular executioners upon detecting DNA damage. Copyright © 2013 Elsevier Inc. All rights reserved.

AB - Abstract Human embryonic stem cells (hESCs) are hypersensitive to apoptotic stimuli, though the underlying mechanisms are poorly characterized. In this issue of Cell Stem Cell, Liu et al. (2013) report that mitochondria of human ESCs exist in an apoptosis-prone state, ready to act as cellular executioners upon detecting DNA damage. Copyright © 2013 Elsevier Inc. All rights reserved.

M3 - Article

SN - 1934-5909

VL - 13

SP - 371

EP - 372

JO - Cell Stem Cell

JF - Cell Stem Cell

ER -

Primed to perish: heightened mitochondrial priming explains hESC apoptosis sensitivity

Abstract

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