TY - JOUR
T1 - Primary Prophylaxis against Pneumocystis carinii Pneumonia
AU - Tarabey, Richard
AU - Schneider, Margriet M.e.
AU - Hoepelman, Andy I.m.
AU - Borleffs, Jan C.c.
PY - 1993/5/20
Y1 - 1993/5/20
N2 - To the Editor: Schneider et al. (Dec. 24 issue)1 concluded that a single dose (either 480 mg or 960 mg) of trimethoprim-sulfamethoxazole once a day is superior to aerosolized pentamidine once a month for the prevention of Pneumocystis carinii pneumonia (PCP) in patients with human immunodeficiency virus (HIV) infection. All the patients had comparable base-line CD4 cell counts. The authors do not report CD4 cell counts for the follow-up period. Zidovudine,2–4 which was used by many patients in this study, may increase the CD4 cell count and therefore diminish the risk of PCP. In the three groups of patients,…
AB - To the Editor: Schneider et al. (Dec. 24 issue)1 concluded that a single dose (either 480 mg or 960 mg) of trimethoprim-sulfamethoxazole once a day is superior to aerosolized pentamidine once a month for the prevention of Pneumocystis carinii pneumonia (PCP) in patients with human immunodeficiency virus (HIV) infection. All the patients had comparable base-line CD4 cell counts. The authors do not report CD4 cell counts for the follow-up period. Zidovudine,2–4 which was used by many patients in this study, may increase the CD4 cell count and therefore diminish the risk of PCP. In the three groups of patients,…
UR - http://www.scopus.com/inward/record.url?scp=0027312020&partnerID=8YFLogxK
U2 - 10.1056/NEJM199305203282019
DO - 10.1056/NEJM199305203282019
M3 - Comment/Letter to the editor
C2 - 8097561
AN - SCOPUS:0027312020
SN - 0028-4793
VL - 328
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 20
ER -