Primary Prevention of Cardiovascular Disease in Asia: Challenges: A Narrative Review

Mayank Dalakoti; Norman H Y Lin; Jonathan Yap; Aaysha Cader; Prajapati Dipanker; Derek Lee; Raja Ezman Raja Shariff; Lucky Cuenza; Satoshi Honda; Vorn Malis; Haowen Jiang; Anish Hirachan; Misato Chimura; Tee Joo Yeo; Khung Keong Yeo; Jack Wei Chieh Tan; Jasper Tromp; Poay Huan Loh; Nicholas W S Chew; Scott Wong; Ching-Hui Sia; Benjamin Y Q Tan; Sofian Johar; Gregory Y H Lip; Eugene Yang; Salim S Virani; Steven Hageman; Hueiming Liu; Emanuele Di Angelantonio; Prabhakaran Dorairaj; Angela S Koh; Calvin Chin; Wael Al Mahmeed; Mark Y Chan; Roger Foo

doi:10.1016/j.jacadv.2025.101670

Primary Prevention of Cardiovascular Disease in Asia: Challenges: A Narrative Review

Mayank Dalakoti^*, Norman H Y Lin, Jonathan Yap, Aaysha Cader, Prajapati Dipanker, Derek Lee, Raja Ezman Raja Shariff, Lucky Cuenza, Satoshi Honda, Vorn Malis, Haowen Jiang, Anish Hirachan, Misato Chimura, Tee Joo Yeo, Khung Keong Yeo, Jack Wei Chieh Tan, Jasper Tromp, Poay Huan Loh, Nicholas W S Chew, Scott WongChing-Hui Sia, Benjamin Y Q Tan, Sofian Johar, Gregory Y H Lip, Eugene Yang, Salim S Virani, Steven Hageman, Hueiming Liu, Emanuele Di Angelantonio, Prabhakaran Dorairaj, Angela S Koh, Calvin Chin, Wael Al Mahmeed, Mark Y Chan, Roger Foo

^*Corresponding author for this work

Internal Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

IMPORTANCE: Asia is home to 60% of the world's population, including the world's two most populous countries, India (1.1B) and China (1.2B). With cardiovascular disease burden and mortality increasing, the role of preventive cardiology is increasingly important.

OBSERVATIONS: The challenges in addressing the cardiovascular disease burden in Asia include unique cardiometabolic features of the different populations, heterogeneity of risk factors among Asian countries, differing levels of health literacy and socioeconomic status, suboptimal infrastructure to support preventive care especially in the primary care sector, high out-of-pocket costs, and environmental pollution.

CONCLUSIONS: Asia is a large continent that comprises diverse populations with varying cultures, socioeconomic status, and health literacy levels. Effective preventive cardiology may require differential health care resource allocation and financing models.

Original language	English
Article number	101670
Number of pages	9
Journal	JACC: Advances
Volume	4
Issue number	4
Early online date	20 Mar 2025
DOIs	https://doi.org/10.1016/j.jacadv.2025.101670
Publication status	Published - Apr 2025

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1-s2.0-S2772963X25000870-mainFinal published version, 1.08 MBLicence: CC BY-NC-ND

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Dalakoti, M., Lin, N. H. Y., Yap, J., Cader, A., Dipanker, P., Lee, D., Raja Shariff, R. E., Cuenza, L., Honda, S., Malis, V., Jiang, H., Hirachan, A., Chimura, M., Yeo, T. J., Yeo, K. K., Tan, J. W. C., Tromp, J., Loh, P. H., Chew, N. W. S., ... Foo, R. (2025). Primary Prevention of Cardiovascular Disease in Asia: Challenges: A Narrative Review. JACC: Advances, 4(4), Article 101670. https://doi.org/10.1016/j.jacadv.2025.101670

@article{c6498b00012d4b398809bc750ef7e635,

title = "Primary Prevention of Cardiovascular Disease in Asia: Challenges: A Narrative Review",

abstract = "IMPORTANCE: Asia is home to 60% of the world's population, including the world's two most populous countries, India (1.1B) and China (1.2B). With cardiovascular disease burden and mortality increasing, the role of preventive cardiology is increasingly important.OBSERVATIONS: The challenges in addressing the cardiovascular disease burden in Asia include unique cardiometabolic features of the different populations, heterogeneity of risk factors among Asian countries, differing levels of health literacy and socioeconomic status, suboptimal infrastructure to support preventive care especially in the primary care sector, high out-of-pocket costs, and environmental pollution.CONCLUSIONS: Asia is a large continent that comprises diverse populations with varying cultures, socioeconomic status, and health literacy levels. Effective preventive cardiology may require differential health care resource allocation and financing models.",

author = "Mayank Dalakoti and Lin, {Norman H Y} and Jonathan Yap and Aaysha Cader and Prajapati Dipanker and Derek Lee and {Raja Shariff}, {Raja Ezman} and Lucky Cuenza and Satoshi Honda and Vorn Malis and Haowen Jiang and Anish Hirachan and Misato Chimura and Yeo, {Tee Joo} and Yeo, {Khung Keong} and Tan, {Jack Wei Chieh} and Jasper Tromp and Loh, {Poay Huan} and Chew, {Nicholas W S} and Scott Wong and Ching-Hui Sia and Tan, {Benjamin Y Q} and Sofian Johar and Lip, {Gregory Y H} and Eugene Yang and Virani, {Salim S} and Steven Hageman and Hueiming Liu and {Di Angelantonio}, Emanuele and Prabhakaran Dorairaj and Koh, {Angela S} and Calvin Chin and {Al Mahmeed}, Wael and Chan, {Mark Y} and Roger Foo",

note = "Publisher Copyright: {\textcopyright} 2025 The Authors",

year = "2025",

month = apr,

doi = "10.1016/j.jacadv.2025.101670",

language = "English",

volume = "4",

journal = "JACC: Advances",

issn = "2772-963X",

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Dalakoti, M, Lin, NHY, Yap, J, Cader, A, Dipanker, P, Lee, D, Raja Shariff, RE, Cuenza, L, Honda, S, Malis, V, Jiang, H, Hirachan, A, Chimura, M, Yeo, TJ, Yeo, KK, Tan, JWC, Tromp, J, Loh, PH, Chew, NWS, Wong, S, Sia, C-H, Tan, BYQ, Johar, S, Lip, GYH, Yang, E, Virani, SS, Hageman, S, Liu, H, Di Angelantonio, E, Dorairaj, P, Koh, AS, Chin, C, Al Mahmeed, W, Chan, MY & Foo, R 2025, 'Primary Prevention of Cardiovascular Disease in Asia: Challenges: A Narrative Review', JACC: Advances, vol. 4, no. 4, 101670. https://doi.org/10.1016/j.jacadv.2025.101670

TY - JOUR

T1 - Primary Prevention of Cardiovascular Disease in Asia

T2 - Challenges: A Narrative Review

AU - Dalakoti, Mayank

AU - Lin, Norman H Y

AU - Yap, Jonathan

AU - Cader, Aaysha

AU - Dipanker, Prajapati

AU - Lee, Derek

AU - Raja Shariff, Raja Ezman

AU - Cuenza, Lucky

AU - Honda, Satoshi

AU - Malis, Vorn

AU - Jiang, Haowen

AU - Hirachan, Anish

AU - Chimura, Misato

AU - Yeo, Tee Joo

AU - Yeo, Khung Keong

AU - Tan, Jack Wei Chieh

AU - Tromp, Jasper

AU - Loh, Poay Huan

AU - Chew, Nicholas W S

AU - Wong, Scott

AU - Sia, Ching-Hui

AU - Tan, Benjamin Y Q

AU - Johar, Sofian

AU - Lip, Gregory Y H

AU - Yang, Eugene

AU - Virani, Salim S

AU - Hageman, Steven

AU - Liu, Hueiming

AU - Di Angelantonio, Emanuele

AU - Dorairaj, Prabhakaran

AU - Koh, Angela S

AU - Chin, Calvin

AU - Al Mahmeed, Wael

AU - Chan, Mark Y

AU - Foo, Roger

PY - 2025/4

Y1 - 2025/4

N2 - IMPORTANCE: Asia is home to 60% of the world's population, including the world's two most populous countries, India (1.1B) and China (1.2B). With cardiovascular disease burden and mortality increasing, the role of preventive cardiology is increasingly important.OBSERVATIONS: The challenges in addressing the cardiovascular disease burden in Asia include unique cardiometabolic features of the different populations, heterogeneity of risk factors among Asian countries, differing levels of health literacy and socioeconomic status, suboptimal infrastructure to support preventive care especially in the primary care sector, high out-of-pocket costs, and environmental pollution.CONCLUSIONS: Asia is a large continent that comprises diverse populations with varying cultures, socioeconomic status, and health literacy levels. Effective preventive cardiology may require differential health care resource allocation and financing models.

AB - IMPORTANCE: Asia is home to 60% of the world's population, including the world's two most populous countries, India (1.1B) and China (1.2B). With cardiovascular disease burden and mortality increasing, the role of preventive cardiology is increasingly important.OBSERVATIONS: The challenges in addressing the cardiovascular disease burden in Asia include unique cardiometabolic features of the different populations, heterogeneity of risk factors among Asian countries, differing levels of health literacy and socioeconomic status, suboptimal infrastructure to support preventive care especially in the primary care sector, high out-of-pocket costs, and environmental pollution.CONCLUSIONS: Asia is a large continent that comprises diverse populations with varying cultures, socioeconomic status, and health literacy levels. Effective preventive cardiology may require differential health care resource allocation and financing models.

U2 - 10.1016/j.jacadv.2025.101670

DO - 10.1016/j.jacadv.2025.101670

M3 - Review article

C2 - 40117691

SN - 2772-963X

VL - 4

JO - JACC: Advances

JF - JACC: Advances

IS - 4

M1 - 101670

ER -

Primary Prevention of Cardiovascular Disease in Asia: Challenges: A Narrative Review

Abstract

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