TY - JOUR
T1 - Prevalence, patterns, and determinants of multimorbidity among childhood and adult cancer survivors
T2 - A systematic review.
AU - Asogwa, Ogechukwu A.
AU - Quansah, Dan Yedu
AU - Boakye, Daniel
AU - Ezewuiro, Obiageli Ntukogu
AU - Boateng, Daniel
N1 - Publisher Copyright:
© 2023 The Authors
PY - 2023/12
Y1 - 2023/12
N2 - Development of multimorbidity is common among cancer survivors due to their previous cancer, treatments, or changes in lifestyle. We summarized evidence on the prevalence, patterns, and determinants of multimorbidity among childhood and adult cancer survivors. We searched PubMed and EMBASE databases for articles reporting prevalence, patterns, and determinants of multimorbidity in cancer survivors. Finally, 23/500 articles were included. There was a large variation in the prevalence of multimorbidity (13–89%) among cancer survivors. Bone marrow transplantation, radiation, female sex, lower level of physical activity, increasing age, minority ethnicity, low-income, and low-education were associated with a higher prevalence of multimorbidity. Patterns of multimorbidity were both concordant and discordant. In conclusion, multimorbidity is highly prevalent and a major concern among cancer survivors. A personalized care plan that takes into account the identified risk may be beneficial to reduce the burden of multimorbidity and improve the quality of life among cancer survivors.
AB - Development of multimorbidity is common among cancer survivors due to their previous cancer, treatments, or changes in lifestyle. We summarized evidence on the prevalence, patterns, and determinants of multimorbidity among childhood and adult cancer survivors. We searched PubMed and EMBASE databases for articles reporting prevalence, patterns, and determinants of multimorbidity in cancer survivors. Finally, 23/500 articles were included. There was a large variation in the prevalence of multimorbidity (13–89%) among cancer survivors. Bone marrow transplantation, radiation, female sex, lower level of physical activity, increasing age, minority ethnicity, low-income, and low-education were associated with a higher prevalence of multimorbidity. Patterns of multimorbidity were both concordant and discordant. In conclusion, multimorbidity is highly prevalent and a major concern among cancer survivors. A personalized care plan that takes into account the identified risk may be beneficial to reduce the burden of multimorbidity and improve the quality of life among cancer survivors.
KW - Cancer survivors
KW - Chronic conditions
KW - Late effects
KW - Multimorbidity
KW - Neoplasms
KW - Patterns
KW - Risk factor
KW - Survivorship
UR - http://www.scopus.com/inward/record.url?scp=85173235240&partnerID=8YFLogxK
U2 - 10.1016/j.critrevonc.2023.104147
DO - 10.1016/j.critrevonc.2023.104147
M3 - Review article
C2 - 37778707
AN - SCOPUS:85173235240
SN - 1040-8428
VL - 192
JO - Critical Reviews in Oncology/Hematology
JF - Critical Reviews in Oncology/Hematology
M1 - 104147
ER -