Preservation of human heart valves for replacement in children with heart valve disease: past, present and future

M. C. Peters; B. P.T. Kruithof; C. V.C. Bouten; I. K. Voets; A. van den Bogaerdt; M. J. Goumans; A. van Wijk

doi:10.1007/s10561-023-10076-2

Preservation of human heart valves for replacement in children with heart valve disease: past, present and future

M. C. Peters^*, B. P.T. Kruithof, C. V.C. Bouten, I. K. Voets, A. van den Bogaerdt, M. J. Goumans, A. van Wijk

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Valvular heart disease affects 30% of the new-borns with congenital heart disease. Valve replacement of semilunar valves by mechanical, bioprosthetic or donor allograft valves is the main treatment approach. However, none of the replacements provides a viable valve that can grow and/or adapt with the growth of the child leading to re-operation throughout life. In this study, we review the impact of donor valve preservation on moving towards a more viable valve alternative for valve replacements in children or young adults.

Original language	English
Pages (from-to)	67-85
Number of pages	19
Journal	Cell and Tissue Banking
Volume	25
Issue number	1
DOIs	https://doi.org/10.1007/s10561-023-10076-2
Publication status	Published - Mar 2024

Keywords

Allograft heart valve
Congenital heart disease
Preservation
Tissue biobanking
Valve replacement

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title = "Preservation of human heart valves for replacement in children with heart valve disease: past, present and future",

abstract = "Valvular heart disease affects 30% of the new-borns with congenital heart disease. Valve replacement of semilunar valves by mechanical, bioprosthetic or donor allograft valves is the main treatment approach. However, none of the replacements provides a viable valve that can grow and/or adapt with the growth of the child leading to re-operation throughout life. In this study, we review the impact of donor valve preservation on moving towards a more viable valve alternative for valve replacements in children or young adults.",

keywords = "Allograft heart valve, Congenital heart disease, Preservation, Tissue biobanking, Valve replacement",

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T2 - past, present and future

AU - Peters, M. C.

AU - Kruithof, B. P.T.

AU - Bouten, C. V.C.

AU - Voets, I. K.

AU - van den Bogaerdt, A.

AU - Goumans, M. J.

AU - van Wijk, A.

N1 - Publisher Copyright: © The Author(s) 2023.

PY - 2024/3

Y1 - 2024/3

N2 - Valvular heart disease affects 30% of the new-borns with congenital heart disease. Valve replacement of semilunar valves by mechanical, bioprosthetic or donor allograft valves is the main treatment approach. However, none of the replacements provides a viable valve that can grow and/or adapt with the growth of the child leading to re-operation throughout life. In this study, we review the impact of donor valve preservation on moving towards a more viable valve alternative for valve replacements in children or young adults.

AB - Valvular heart disease affects 30% of the new-borns with congenital heart disease. Valve replacement of semilunar valves by mechanical, bioprosthetic or donor allograft valves is the main treatment approach. However, none of the replacements provides a viable valve that can grow and/or adapt with the growth of the child leading to re-operation throughout life. In this study, we review the impact of donor valve preservation on moving towards a more viable valve alternative for valve replacements in children or young adults.

KW - Allograft heart valve

KW - Congenital heart disease

KW - Preservation

KW - Tissue biobanking

KW - Valve replacement

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Preservation of human heart valves for replacement in children with heart valve disease: past, present and future

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