TY - JOUR
T1 - Prenatal assessment of brain malformations on neuroimaging
T2 - an expert panel review
AU - Pogledic, Ivana
AU - Mankad, Kshitij
AU - Severino, Mariasavina
AU - Lerman-Sagie, Tally
AU - Jakab, Andras
AU - Hadi, Efrat
AU - Jansen, Anna C
AU - Bahi-Buisson, Nadia
AU - Di Donato, Natalya
AU - Oegema, Renske
AU - Mitter, Christian
AU - Capo, Ivan
AU - Whitehead, Matthew T
AU - Haldipur, Parthiv
AU - Mancini, Grazia
AU - Huisman, Thierry A G M
AU - Righini, Andrea
AU - Dobyns, Bill
AU - Barkovich, James A
AU - Jovanov Milosevic, Natasa
AU - Kasprian, Gregor
AU - Lequin, Maarten
N1 - Publisher Copyright:
© 2024 The Author(s).
PY - 2024/12
Y1 - 2024/12
N2 - Brain malformations represent a heterogeneous group of abnormalities of neural morphogenesis, often associated with aberrations of neuronal connectivity and brain volume. Prenatal detection of brain malformations requires a clear understanding of embryology and developmental morphology through the various stages of gestation. This expert panel review is written with the central aim of providing an easy-to-understand road map to improve prenatal detection and characterization of structural malformations based on the current understanding of normal and aberrant brain development. For every developmental stage, the utility of each available neuroimaging modality, including prenatal multiplanar neuro sonography, anatomical MRI and advanced MRI techniques, as well as further insights from post-mortem imaging, has been highlighted.
AB - Brain malformations represent a heterogeneous group of abnormalities of neural morphogenesis, often associated with aberrations of neuronal connectivity and brain volume. Prenatal detection of brain malformations requires a clear understanding of embryology and developmental morphology through the various stages of gestation. This expert panel review is written with the central aim of providing an easy-to-understand road map to improve prenatal detection and characterization of structural malformations based on the current understanding of normal and aberrant brain development. For every developmental stage, the utility of each available neuroimaging modality, including prenatal multiplanar neuro sonography, anatomical MRI and advanced MRI techniques, as well as further insights from post-mortem imaging, has been highlighted.
KW - brain
KW - fetal MRI
KW - fetal ultrasound
KW - malformations of cortical development
KW - neuroimaging
U2 - 10.1093/brain/awae253
DO - 10.1093/brain/awae253
M3 - Article
C2 - 39054600
SN - 0006-8950
VL - 147
SP - 3982
EP - 4002
JO - Brain : a journal of neurology
JF - Brain : a journal of neurology
IS - 12
ER -