TY - JOUR
T1 - Power reflectance as a screening tool for the diagnosis of superior semicircular canal dehiscence
AU - Merchant, Gabrielle R.
AU - Roösli, Christof
AU - Niesten, Marlien E F
AU - Hamade, Mohamad A.
AU - Lee, Daniel J.
AU - McKinnon, Melissa L.
AU - Ulku, Cagatay H.
AU - Rosowski, John J.
AU - Merchant, Saumil N.
AU - Nakajima, Hideko Heidi
PY - 2015/1/20
Y1 - 2015/1/20
N2 - Hypothesis: Power reflectance (PR) measurements in ears with superior canal dehiscence (SCD) have a characteristic pattern, the detection of which can assist in diagnosis.Background: The aim of this study was to determine whether PR coupled with a novel detection algorithm can perform well as a fast, noninvasive, and easy screening test for SCD. The screening test aimed to determine whether patients with various vestibular and/or auditory symptom(s) should be further considered for more expensive and invasive tests that better define the diagnosis of SCD (and other third-window lesions).Methods: Power reflectance was measured in patients diagnosed with SCD by high-resolution computed tomography. The study included 40 ears from 32 patients with varying symptoms (e.g., with and without conductive hearing loss, vestibular symptoms, and abnormal auditory sensations).Results: Power reflectance results were compared to previously published norms and showed that SCD is commonly associated with a PR notch near 1 kHz. An analysis algorithm was designed to detect such notches and to quantify their incidence in affected and normal ears. Various notch detection thresholds yielded sensitivities of 80% to 93%, specificities of 69% to 72%, negative predictive values of 84% to 93%, and a positive predictive value of 67%.Conclusion: This study shows evidence that PR measurements together with the proposed notch-detecting algorithm can be used to quickly and effectively screen patients for thirdwindow lesions such as SCD in the early stages of a diagnostic workup.
AB - Hypothesis: Power reflectance (PR) measurements in ears with superior canal dehiscence (SCD) have a characteristic pattern, the detection of which can assist in diagnosis.Background: The aim of this study was to determine whether PR coupled with a novel detection algorithm can perform well as a fast, noninvasive, and easy screening test for SCD. The screening test aimed to determine whether patients with various vestibular and/or auditory symptom(s) should be further considered for more expensive and invasive tests that better define the diagnosis of SCD (and other third-window lesions).Methods: Power reflectance was measured in patients diagnosed with SCD by high-resolution computed tomography. The study included 40 ears from 32 patients with varying symptoms (e.g., with and without conductive hearing loss, vestibular symptoms, and abnormal auditory sensations).Results: Power reflectance results were compared to previously published norms and showed that SCD is commonly associated with a PR notch near 1 kHz. An analysis algorithm was designed to detect such notches and to quantify their incidence in affected and normal ears. Various notch detection thresholds yielded sensitivities of 80% to 93%, specificities of 69% to 72%, negative predictive values of 84% to 93%, and a positive predictive value of 67%.Conclusion: This study shows evidence that PR measurements together with the proposed notch-detecting algorithm can be used to quickly and effectively screen patients for thirdwindow lesions such as SCD in the early stages of a diagnostic workup.
KW - Admittance
KW - Energy reflectance
KW - Power reflectance
KW - Reflectance
KW - Superior canal dehiscence
KW - Superior semicircular canal dehiscenceVWideband acoustic immittance.
UR - http://www.scopus.com/inward/record.url?scp=84919479052&partnerID=8YFLogxK
U2 - 10.1097/MAO.0000000000000294
DO - 10.1097/MAO.0000000000000294
M3 - Article
C2 - 25076227
AN - SCOPUS:84919479052
SN - 1531-7129
VL - 36
SP - 172
EP - 177
JO - Otology & Neurotology
JF - Otology & Neurotology
IS - 1
ER -