Potential improvement of pregnancy outcome through prenatal small for gestational age detection. [correction]

Bart Jan Voskamp, Daphne H Beemsterboer, Corine J M Verhoeven, Katrien Oude Rengerink, Anita C J Ravelli, Jannet J H Bakker, Ben Willem J Mol, Eva Pajkrt, K Oude Rengerink

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

OBJECTIVE: To assess differences in mode of delivery and pregnancy outcome between prenatally detected and nonprenatally detected small for gestational age (SGA) neonates born at term.

STUDY DESIGN: We performed a retrospective multicenter cohort study. All singleton infants, born SGA in cephalic position between 36(0/7) and 41(0/7) weeks gestation, were classified as either prenatally detected SGA or nonprenatally detected SGA. With propensity score matching we created groups with comparable baseline characteristics. We compared these groups for composite adverse perinatal outcome, labor induction, and cesarean section rates.

RESULTS: We included 718 SGA infants, of whom 555 (77%) were not prenatally detected. Composite adverse neonatal outcome did not differ statistically significant between the matched prenatally detected and the nonprenatally detected group (5.5 vs. 7.4%, odds ratio [OR] 0.74, 95% confidence interval [CI]: 0.30-1.8). However, perinatal mortality only occurred in the nonprenatally detected group (1.8% [3/163] in the matched cohort, 1.3% [7/555] in the complete cohort). In the propensity matched prenatally detected SGA group both induction of labor (57 vs. 9%, OR 14.0, 95% CI: 7.4-26.2) and cesarean sections (20 vs. 8%, OR 2.9, 95% CI: 1.5-5.8) were more often performed compared with the nonprenatally detected SGA group.

CONCLUSION: Prenatal SGA detection at term allows timely induction of labor and cesarean sections thus potentially preventing stillbirth.

Original languageEnglish
Pages (from-to)1093-104
Number of pages12
JournalAmerican Journal of Perinatology
Volume31
Issue number12
DOIs
Publication statusPublished - Dec 2014

Keywords

  • Adult
  • Birth Weight
  • Cesarean Section
  • Delivery, Obstetric
  • Extraction, Obstetrical
  • Female
  • Fetal Death
  • Humans
  • Infant
  • Infant Death
  • Infant, Newborn
  • Infant, Small for Gestational Age
  • Labor, Induced
  • Male
  • Perinatal Mortality
  • Pregnancy
  • Prenatal Diagnosis
  • Retrospective Studies
  • Stillbirth
  • Term Birth
  • Young Adult

Fingerprint

Dive into the research topics of 'Potential improvement of pregnancy outcome through prenatal small for gestational age detection. [correction]'. Together they form a unique fingerprint.

Cite this