Polytrauma: update on basic science and clinical evidence

Aaron Nauth; Frank Hildebrand; Heather Vallier; Timothy Moore; Luke Leenen; Todd McKinley; Hans Christoph Pape

doi:10.1097/OI9.0000000000000116

Polytrauma: update on basic science and clinical evidence

Aaron Nauth^*
, Frank Hildebrand
, Heather Vallier
, Timothy Moore
, Luke Leenen
, Todd McKinley
, Hans Christoph Pape

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

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Abstract

AbstractThe management of multiply injured or severely injured patients is a complex and dynamic process. Timely and safe fracture fixation is a critical component of the multidisciplinary care that these patients require. Effective management of these patients, and their orthopaedic injuries, requires a strong understanding of the pathophysiology of the response to trauma and indicators of patient status, as well as an appreciation for the dynamic nature of these parameters. Substantial progress in both clinical and basic science research in this area has advanced our understanding of these concepts and our approach to management of the polytraumatized patient. This article summarizes a symposium on this topic that was presented by an international panel of experts at the 2020 Virtual Annual Meeting of the Orthopaedic Trauma Association.

Original language	English
Article number	E116
Number of pages	6
Journal	OTA International
Volume	4
Issue number	1
DOIs	https://doi.org/10.1097/OI9.0000000000000116
Publication status	Published - 23 Mar 2021

Keywords

damage control surgery
early appropriate care
inflammation
neutrophil
polytrauma

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10.1097/OI9.0000000000000116Licence: CC BY-NC-ND

Polytrauma: update on basic science and clinical evidenceFinal published version, 1.21 MBLicence: CC BY-NC-ND

https://pmc.ncbi.nlm.nih.gov/articles/PMC8016602/Licence: CC BY-NC-ND

Cite this

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abstract = "AbstractThe management of multiply injured or severely injured patients is a complex and dynamic process. Timely and safe fracture fixation is a critical component of the multidisciplinary care that these patients require. Effective management of these patients, and their orthopaedic injuries, requires a strong understanding of the pathophysiology of the response to trauma and indicators of patient status, as well as an appreciation for the dynamic nature of these parameters. Substantial progress in both clinical and basic science research in this area has advanced our understanding of these concepts and our approach to management of the polytraumatized patient. This article summarizes a symposium on this topic that was presented by an international panel of experts at the 2020 Virtual Annual Meeting of the Orthopaedic Trauma Association.",

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AU - Nauth, Aaron

AU - Hildebrand, Frank

AU - Vallier, Heather

AU - Moore, Timothy

AU - Leenen, Luke

AU - McKinley, Todd

AU - Pape, Hans Christoph

PY - 2021/3/23

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N2 - AbstractThe management of multiply injured or severely injured patients is a complex and dynamic process. Timely and safe fracture fixation is a critical component of the multidisciplinary care that these patients require. Effective management of these patients, and their orthopaedic injuries, requires a strong understanding of the pathophysiology of the response to trauma and indicators of patient status, as well as an appreciation for the dynamic nature of these parameters. Substantial progress in both clinical and basic science research in this area has advanced our understanding of these concepts and our approach to management of the polytraumatized patient. This article summarizes a symposium on this topic that was presented by an international panel of experts at the 2020 Virtual Annual Meeting of the Orthopaedic Trauma Association.

AB - AbstractThe management of multiply injured or severely injured patients is a complex and dynamic process. Timely and safe fracture fixation is a critical component of the multidisciplinary care that these patients require. Effective management of these patients, and their orthopaedic injuries, requires a strong understanding of the pathophysiology of the response to trauma and indicators of patient status, as well as an appreciation for the dynamic nature of these parameters. Substantial progress in both clinical and basic science research in this area has advanced our understanding of these concepts and our approach to management of the polytraumatized patient. This article summarizes a symposium on this topic that was presented by an international panel of experts at the 2020 Virtual Annual Meeting of the Orthopaedic Trauma Association.

KW - damage control surgery

KW - early appropriate care

KW - inflammation

KW - neutrophil

KW - polytrauma

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JO - OTA International

JF - OTA International

IS - 1

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ER -

Polytrauma: update on basic science and clinical evidence

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Keywords

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