Plaveiselcelcarcinoom bij lichen sclerosus van de penis

Translated title of the contribution: Squamous cell carcinoma in penile lichen sclerosus

E. M. Van Der Snoek, S. M. Couwenberg, J. A. Kummer, J. S. De Beij, M. T.W.T. Lock

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Abstract

Anogenital lichen sclerosus is usually regarded as premalignant condition. Research on malignant degeneration in women with LS shows percentages between 3 and 10%. Less is known about LS in men. Analysis of four clinical studies in the period 1997 to 2006 on carcinomata in penile LS shows a life-time risk of about 8% (range 6.3 to 12.5%). The risk of malignant degeneration in LS is therefore probably comparable in women and men. The average lag time from onset of penile LS to cancer development is an estimated 18 years. Human papillomavirus may play an important role in this degeneration. Based on a case history, the literature on penile carcinomata is reviewed in this article.

Translated title of the contributionSquamous cell carcinoma in penile lichen sclerosus
Original languageDutch
Pages (from-to)406-409
Number of pages4
JournalNederlands Tijdschrift voor Dermatologie en Venereologie
Volume18
Issue number10
Publication statusPublished - Dec 2008

Keywords

  • Lichen sclerosus
  • Penis
  • Squamous cell carcinoma

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